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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Evaluation of the Ability of an Organic Derivative of Ruthenium(II) to Reinforce the Cytotoxicity of Fast Neutron Against Malignant Cells in Culture
- Source: Letters in Drug Design & Discovery, Volume 5, Issue 1, Jan 2008, p. 1 - 6
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- 01 Jan 2008
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Abstract
The effect of combining RDC-11 (a new ruthenium organometallic complex) and fast neutrons (high-LET radiations) has been evaluated in RDM4 and U-87 tumor cell lines. After co-treatment, a substantial reduction of cell growth was recorded, which appears not to be correlated with the induction of apoptosis.
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