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- ISSN: 1570-1808
- E-ISSN: 1875-628X
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Design and Synthesis of Combinatorial Scaffolds-Diazepinone and Homopiperazine
- Source: Letters in Drug Design & Discovery, Volume 2, Issue 1, Feb 2005, p. 48 - 50
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- 01 Feb 2005
Abstract
A general method for the construction of diazepinone and homopiperazine scaffolds has been developed by utilizing Beckmann rearrangement as the key step in the design. Using this methodology, the synthesis of a diverse diazepinone library with three points of diversity has been achieved starting from readily available 4-piperidone.
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