Recent Patents on Vascular Stent Material and Its Preparation

Background: A vascular stent is a kind of internal stent implanted in the lesion segment when the vessel is stenosis or pathologically expanded, but thee will be stenosis complications in the long term after stent implantation. Therefore, the ideal vascular stent material should have good tissue and blood compatibility, which is the key to controlling the stent in the occurrence of stenosis. Besides, it should have good biodegradability, non-toxicity, and good mechanical properties. It should be smooth and flexible enough, and the stent should have good compliance when implanted in the human body. It should also have biological properties and physiological characteristics that are close to normal blood vessels to ensure that cells can be well attached and grown to avoid any adverse immune exclusion or post-metabolism. The resulting undesirable products should be widely available and inexpensive and can be produced on a large scale to meet different clinical needs. Objective: To solve the long-term complications of stenosis after vascular stent placement, the vascular stent material and its preparation have been continuously optimized and improved. Methods: A review of various representative patents and papers on vascular stent materials and their preparation at home and abroad are reviewed. Results: By summarizing a large number of vascular stent materials and their preparation patents and papers, the preparation methods of vascular stents, the optimization of preparation methods, the performance of vascular stents, and the development trend of vascular stent materials and their preparation are discussed. Conclusion: The preparation method of the vascular stent material and the optimization of the structure are beneficial to improving the performance of the vascular stent material. More related patents and papers will appear in the future.