Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets - Immune, Endocrine & Metabolic Disorders) - Volume 22, Issue 11, 2022

Endocrine disruptors are natural or man-made chemicals that interfere with the body’s endocrine system leading to hormone synthesis and production defects. These chemicals are categorized as plasticizers and cosmetic chemicals, heavy metals, phytoestrogens, pesticides, detergents, surfactants, and flame retardants. Some of the most common endocrine disruptors are dioxins, bisphenol A, phthalates, perchlorate, pe Read More

Cancer of the female reproductive system involves abnormal cell growth that can potentially invade the peritoneal cavity resulting in malignancy and disease severity. Ovarian cancer is the most common type of gynecological cancer, which often remains undiagnosed until the later stages of the disease or until cancer has metastasized towards the peritoneum and omentum, compelling it to be a deadly disease complicating t Read More

The COVID-19 illness is a highly contagious disease presently affecting more than 200 countries caused by the SARS-CoV-2 coronavirus (Severe Acute Respiratory Syndrome Coronavirus-2). Persons with diabetes mellitus (DM), severe obesity, cardiovascular disease, and hypertension are more likely to be infected with COVID-19 and are at a higher risk of death. The COVID-19 pandemic is overlapping the preexisting diabet Read More

Breast cancer, even today, can cause death. Therefore, prevention and early detection are fundamental factors. The mechanisms that favour it are genetic and epigenetic, and seem to play a significant role; also, the microbiota can change estrogen levels and can induce chronic inflammation in the neoplastic site, alternating the balance between proliferation and cell death. Activated steroid hormone receptors in Read More

Background: Non-alcoholic fatty liver disease is a common chronic liver injury disease, and its incidence is rapidly increasing across the globe, thus becoming a serious threat to human health. So far, the clinical prevention and treatment of non-alcoholic fatty liver disease mainly include single-targeted drug therapy, surgical treatment and lifestyle changes. However, these treatments cannot completely address the complex pa Read More