Achillea millefolium E.Mey: Phytochemistry and Pharmacological Profile

A staggering 80% of the population in developing countries relies on herbal medicine for treatment of various diseases and disorders. Among them, Achillea millifolium from Asteraceae family is one medicinally important plant called as “yarrow” and reported as being used in folklore medicine for ailments such as skin inflammations, spasmodic and gastrointestinal disorders, as well as hepatobiliary complaints. Therefore, a plethora of scientific studies have been conducted to give substance to its ethnomedicinal claims, and in addition to that, even more, biological functions such as its hypotensive, antioxidant, antimicrobial, vasoprotective, antiulcer and antis-permatogenic activities, scientifically established. Our review comprehensively collects recent phytochemical and pharmacological activities of Achillea millifolium and should, therefore, act a suitable reference for future research into the plant’s phytochemical profiling and overall pharmacological evaluation.