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2000
Volume 16, Issue 2
  • ISSN: 1874-4710
  • E-ISSN: 1874-4729

Abstract

In recent years, there has been an increased interest in 44Ti/44Sc generators as an onsite source of 44Sc for medical applications without needing a proximal cyclotron. The relatively short half-life (3.97 hours) and high positron branching ratio (94.3%) of 44Sc make it a viable candidate for positron emission tomography (PET) imaging. This review discusses current 44Ti/44Sc generator designs, focusing on their chemistry, drawbacks, post-elution processing, and relevant preclinical studies of the 44Sc for potential PET radiopharmaceuticals.

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/content/journals/crp/10.2174/1874471016666221111154424
2023-06-01
2025-05-09
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/content/journals/crp/10.2174/1874471016666221111154424
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  • Article Type:
    Review Article
Keyword(s): diagnostics; generators; PET; radioisotope production; radiolabeling; Scandium; titanium
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