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Volume 18, Issue 2
  • ISSN: 1874-4710
  • E-ISSN: 1874-4729

Abstract

Background

Various types of radiosensitisers have been introduced from the past until the present day for applications in the biomedical field. However, there is a lack of understanding and comparison between the various parameters introduced in addition to a lack of consensus among researchers on the optimal radiosensitiser for applications in the biomedical field.

Objective

This review aimed to investigate the usage of radiosensitisers in the biomedical field, determine their important parameters, and suggest radiosensitisers with potential among the analysed radiosensitisers.

Results and Conclusion

This review has discussed several parameters for radiosensitisers, including median lethal dose, cell survival, tumour size, cell viability, Dose Enhancement Factor (DEF), Reactive Oxygen Species (ROS) concentration, radiosensitiser production complexity, radiosensitiser administration technique, and radiosensitiser toxicity. General trends regarding the development of radiosensitisers, including the types, effectiveness, and their production complexity, have also been discussed within this review article.

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2024-09-02
2025-07-04

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/content/journals/crp/10.2174/0118744710269842240825160247
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An Analysis of the Radiosensitiser Applications in the Biomedical Field
Current Radiopharmaceuticals 18, 81 (2025); https://doi.org/10.2174/0118744710269842240825160247
/content/journals/crp/10.2174/0118744710269842240825160247
/content/journals/crp/10.2174/0118744710269842240825160247
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  • Article Type:     Review Article
Keyword(s): dose enhancement; effectiveness; gold nanoparticles; production complexity; Radiosensitiser; toxicity

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