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Current Respiratory Medicine Reviews - Online First
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Clinical Characteristics and Outcomes in Tracheobronchopathia Osteochondroplastica: A Scoping Review
Available online: 24 October 2024More LessBackground and ObjectiveTracheobronchopathia osteochondroplastica (TBOCP) is a rare, benign condition characterised by the presence of multiple bony and cartilaginous nodules in the tracheal and bronchial submucosa. Its etiology remains unknown, and clinical presentations and management vary.
MethodsWe conducted a scoping review to evaluate clinical and radiological characteristics, diagnostic investigations and prognostic outcomes of TBOCP in adults by exploring Pubmed and SCOPUS databases.
ResultsFrom the search results of 675 studies, 98 were included in this scoping review. TBOCP has a myriad of presenting symptoms and clinical severity but is notably an asthma mimic, displaying an obstructive pattern on spirometry. Bronchoscopic tools were the most common interventional diagnostic or management tool.
ConclusionWhile the etiology of TBOCP remains unknown, clinicians are alerted to its varied presentations and classical histopathological and gross morphological appearance.
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Asthma: An Overview of Pathophysiology, Molecular Mechanisms and Combination Therapy
Authors: S Sneha and Ekta SinghAvailable online: 15 October 2024More LessAsthma is a chronic inflammatory disorder of the respiratory airways that is characterized by narrowing of airways, wheezing, difficulty in respiration, shortness of breath, stiffness in the chest region, and sometimes cough. In some cases, mucus secretion is enhanced. Several factors precipitate asthma. These factors may contribute individually or collectively to the pathophysiology of asthma. The objective of this review is to compile a detailed description of pathways involved in asthma. This compilation helps provide a better understanding of the disease. The information provided in this review may be used for planning a personalized therapy. Besides pathways, this review includes the current therapy used for asthma management. New combinations of drugs targeting multiple pathways can be developed to better manage the disease.
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Approaches to Improve the Sleep Quality in Long Covid Patients: A Systematic Review
Authors: Soheila ShamsiKhani and Mahsa HosseiniAvailable online: 08 October 2024More LessBackgroundGiven the high prevalence of Long COVID, sleep problems have emerged as a significant issue for individuals after COVID-19 infection, potentially impacting their quality of life.
ObjectiveOur study aims to identify effective strategies for improving sleep quality and offers recommendations for future research.
MethodsThe present systematic review study investigated ways to improve sleep quality in Long COVID patients. The study was conducted according to the updated PRISMA guidelines. The risk of bias was assessed using ROB 2.0.
ResultsFinally, six articles were included in the present study to identify strategies for improving and enhancing sleep quality in Long COVID. The results of the present study indicate that various interventions have been carried out to improve sleep quality, including psychological, cognitive, and physical factors related to long-term COVID-19 conditions.
ConclusionBased on existing evidence, interventions such as mind meditation, yoga, and hyperbaric oxygen therapy have demonstrated efficacy in enhancing sleep quality among Long COVID patients.
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