Current Psychiatry Research and Reviews - Volume 15, Issue 1, 2019

Background: Although the relationship between the occurrence of suicide and the presence of psychosocial suffering in bereaved relatives is clear, there are still few studies that deal with the detail of these repercussions and the therapeutic conduction given to them for the suicide. Objective: to carry out an integrative review on the psychopathological and psychosocial repercussions of suicide in the family, with emphasis on the detail of the main psychopathological characteristics presented by the individuals and the psychosocial impacts of mourning. Method: An integrative review was performed. The guiding question considered Population Intervention Comparator Outcome Setting and the revision protocol is in agreement with Preferred Reporting Items for Systematic Reviews and Meta-Analyzes. The search occurred in the bases: Periodicals CAPES, PsycINFO and PubMed. Original articles were included, without language restriction that emphasized psychopathological and psychosocial aspects of the mourners after suicide. We excluded review studies, clinical cases, editorials and retrospectives. Results: The process of suicide mourning for family members is a complex event, marked by stigma and can predispose patients to mental illness and suicidal behavior, especially in the early years of mourning. In addition, it is necessary to expand the scope of evidence on the effectiveness of support and intervention with this population. Conclusion: Bereaved families need specialized preventive support insofar as the complexity of bereavement becomes a vulnerability factor for mental illness.

Background: Thought records are a core component of Cognitive Behavior Therapy. Over time, thought records have been modified to suit various needs or preferences. A diversity of thought records have been developed, which include differing components and cognitive change strategies. Yet, due to a lack of specificity in the literature and field, different thought records are often treated as though they are interchangeable. Limited extant literature suggests that differing thought records may have unique clinical effects. However, meta-analyzing the comparable or differing effects of the distinct extant thought records is impeded by the lack of a coding system for thought records. Objective: The current study sought to prepare a way for further understanding the differential utility and effectiveness of different iterations of thought records by creating a coding system, which is described in detail. This coding system will be used to guide future research into which thought records work best for which problems. Method: Thought records were gathered from seminal texts and solicited from the certified members of the Academy of Cognitive Therapy and the American Board of Behavioral and Cognitive Psychology. Results: In total, 110 non-identical thought records were gathered and coded into 55 unique combinations. These results demonstrate that the variability of thought records used by qualified therapists extends well beyond those found in seminal CBT texts. Conclusion: This broad diversity justifies the need for a coding system to inform future lines of research.

Background: Due to the increase in life expectancies and the number of aging population worldwide, there is a rise of aging diseases, out of which the most common is dementia. Therefore, researchers all over the world look for another alternative ways that can improve cognitive competency and neuropsychiatric disorders of these people in order to assist them in maintaining the quality of their life and reducing the overall economic burden. One of the alternative approache seems to be non-pharmacological therapies, which are non-invasive, with minimum side effects and definitely less costly, such as a music therapy (MT). Objective: The purpose of this review study is to discuss benefits and limitations of music therapy in the management of dementia. Method: This was done by conducting a literature review of available sources found in the Web of Science, Scopus and MEDLINE. Results: The findings show that MT may be a promising non-invasive strategy with a long history of use, relatively favorable acceptance among patients with dementia, and its efficacy especially in the treatment of psycho-behavioral symptoms of dementia. Conclusion: However, more research should be conducted in the area of cognitive functioning, as well as on the mechanism of MT for dementia patients.

Background: Patients with schizophrenia show not only cognitive, but also perceptual deficits. Perceptual deficits may affect different sensory modalities. Among these, the impairment of visual information processing is of particular relevance as demonstrated by the high incidence of visual disturbances. In recent years, the study of neurophysiological mechanisms that underlie visuo-perceptual, -spatial and -motor disorders in schizophrenia has increasingly attracted the interest of researchers. Objective: The study aims to review the existent literature on magnocellular/dorsal (occipitoparietal) visual processing stream impairment in schizophrenia. The impairment of relatively early stages of visual information processing was examined using experimental paradigms such as backward masking, contrast sensitivity, contour detection, and perceptual closure. The deficits of late processing stages were detected by examining visuo-spatial and -motor abilities. Results: Neurophysiological and behavioral studies support the existence of deficits in the processing of visual information along the magnocellular/dorsal pathway. These deficits appear to affect both early and late stages of visual information processing. Conclusion: The existence of disturbances in the early processing of visual information along the magnocellular/dorsal pathway is strongly supported by neurophysiological and behavioral observations. Early magnocellular dysfunction may provide a substrate for late dorsal processing impairment as well as higher-level cognition deficits.

Background: The major depressive disorder (MDD) is a chronic illness with major manifestations in cognitive, social and occupational functions. The pathophysiological model is an intrigue issue for scientists to understand the origin of MDD. Objective: In the beginning, the cortico-limbic-striato-pallidal-thalamic model has been proposed to link the clinical symptoms with the abnormalities in brain structure and function. However, the model is still evolving due to recent advances in the neuroimaging techniques, especially for functional magnetic resonance imaging (fMRI). The recent findings in the fMRI studies in MDD showed the importance of fronto-limbic model for the modulations between cognitive function and primitive and negative emotions. Method: This review will focus on the literature of fMRI studies in MDD with findings not in the fronto-limbic structures. Results: Additional regions beyond the fronto-limbic model have been observed in some literature of MDD. Some regions in the parietal, temporal and occipital lobes have been shown with the alterations in gray matter, white matter and brain function. The importance of sensory detection, visuospatial function, language reception, motor response and emotional memories in these regions might provide the clues to understand the cognitive misinterpretations related to altered reception of outside information, behavioral responses related to biased cognition and emotional memories and clinical symptoms related to the significant alterations of interactions between different brain regions. Conclusion: Future studies to establish a more comprehensive model for MDD will be warranted, especially for the model beyond the fronto-limbic structures.

Due to the growth of life expectancies and the increasing number of elderly population all over the world, there is a risk of growth of aging diseases such as dementia. Recent research studies also indicate that there will be a growing number of military veterans who will be affected by dementia, already at the age of 55+ years. In the case of combat military personnel, the most common dementias are Alzheimer’s disease and vascular dementia. These two dementias are very similar because their main symptoms are the same. The purpose of this review is to explore two main risk factors influencing the development of the dementias. These include posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI). Furthermore, the authors of this study focus on the exploration of the treatment of PTSD and TBI in order to delay the development of dementias among combat military personnel. For the purpose of this study, a method of literature review of available sources exploring these two main risk factors of dementia among combat military personnel was used. Based on the evaluation of these literature sources, possibilities of pharmacological and non-pharmacological approaches to the treatment and care of these people were described.

Background: Down syndrome (DS) is associated with a high prevalence of cognitive impairment and dementia in middle age and older adults. Given the presence of common neuropathological findings and similar pathogenic mechanisms, dementia in DS is regarded as a form of genetically determined, early-onset AD. The clinical characterization of cognitive decline in persons with DS is a difficult task, due to the presence intellectual disability and pre-existing cognitive impairment. Subtle changes that occur at early stages of the dementing process may not be perceived clinically, given that most cognitive screening tests are not sensitive enough to detect them. Therefore, biological markers will provide support to the diagnosis of DS-related cognitive impairment and dementia, particularly at early stages of this process. Objective: To perform a systematic review of the literature on AD-related biomarkers in DS. Method: We searched PubMed, Web of Science and Cochrane Library for scientific papers published between 2008 and 2018 using as primary mesh terms ‘Down’, ‘Alzheimer’, ‘biomarker’. Results: 79 studies were retrieved, and 39 were considered eligible for inclusion in the systematic review: 14 post-mortem studies, 10 neuroimaging, 4 addressing cerebrospinal fluid biomarkers, and 11 on peripheral markers. Conclusion: There is consistent growth in the number of publication in this field over the past years. Studies in DS-related dementia tend to incorporate many of the diagnostic technologies that have been more extensively studied and validated in AD. In many instances, the study of CNS and peripheral biomarkers reinforces the presence of AD pathology in DS.

Racial discrimination is a commonly experienced stressor among African American that occurs in various forms. The stressful qualities of racial discrimination are highlighted by how such events are often cognitively appraised and the negative mental health outcomes associated with such racial stressors. Traditionally, existing conceptual models of racial discrimination have characterized the reactive experiences of African Americans, particularly identifying how African American typically respond cognitively, emotionally, and behaviorally. Moving forward, it is vital that the conceptual models of racial discrimination extend beyond the reactive experience and further identify nuances in the anticipatory and preparatory processes associated with racial discrimination. As such, the current review draws upon a model of proactive coping (Aspinwall & Taylor, 1997) to begin conceptualizes how African American may cope with anticipated discriminatory experiences and propose future research directions for generating conceptual models that more comprehensively capture experiences of racial stress among African Americans.