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Special Health Care Needs in Internationally Adopted Children: Prevalence of Chronic Conditions and Interesting Origin-correlated Risk Factors
Authors: Signorelli Benedetta, Lisi Catiuscia, Galli Luisa and Chiappini ElenaAvailable online: 17 April 2025More LessIntroductionThe Federal Maternal and Child Health Bureau defines Children with special health care needs (CSHCN) as those who have, or are at increased risk for, chronic physical, developmental, behavioral, or emotional conditions, and require health and related services beyond what is generally required by other children. More than half of the entire Italian internationally adopted children (IAC) population has special nee Read More
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Parvovirus B19 Intrauterine Infection and Cerebral Cortical Dysplasia: A Case Report
Available online: 14 April 2025More LessBackground Intrauterine parvovirus B19 infection usually causes fetal anemia, hydrops, and stillbirth. Less commonly, central nervous system injuries have also been described. Case Presentation We report an atypical case of severe brain injury with diffuse malformation of cortical development and severely immature gyration in a preterm infant with profound fetal anemia and hydrops due to congenital parvovirus Read More
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The Role of Immune Markers in Predicting Infectious Complications in Children with Congenital Heart Defects
Available online: 26 March 2025More LessThe literature review presents data from a limited number of available studies conducted over the last two decades on immunological deficiency in congenital heart defects (CHDs), which is the cause of frequent infectious complications before and after cardiac surgery. Several studies based on screenings at various levels indicate the presence of primary and secondary immunodeficiency in CHDs, in particular about 13 genetic s Read More
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Parental Knowledge and Attitudes Towards Antibiotic Resistance in Children: A Review Article
Authors: Majd Masadeh, Sabariah Noor Harun, Tareq Mukattash and Nasr AlrabadiAvailable online: 12 February 2025More LessAntibiotic misuse among children continues to be one of the major critical public health issues worldwide, particularly in developing countries such as Jordan. Incorrect antibiotic use is hugely influenced by parents' knowledge and attitudes on the subject at hand. This review, therefore, seeks to establish the current state of parental knowledge and attitudes toward antibiotics in Jordanian children, with particular emphasis on thos Read More
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Aberrant Expressions of EDNRB and EDN3 in a Multifactorial Hirschsprung Disease
Available online: 22 January 2025More LessBackground Hirschsprung disease (HSCR) is a multifactorial disorder due to the enteric nervous system (ENS) development failure. At least 35 genes have been responsible for HSCR, including EDNRB and EDN3. Here, we aimed to determine the EDRNB and EDN3 expressions effects in HSCR subjects. Methods Our study analyzed EDNRB and EDN3 expressions in the colon of HSCR subjects and controls by a quantitative PCR. Th Read More
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GeneXpert MTB/RIF Ultra in Pediatric Tuberculosis: How Disease Characteristics Modify Test Performances
Authors: Domenico Pace, Roberta Pellegrino, Irene Dalpiaz, Marco Renni, Luisa Galli and Elena ChiappiniAvailable online: 06 January 2025More LessIntroduction The diagnosis of pediatric tuberculosis (TB) is challenging, due to the lower sensitivity of microbiological tests, such as culture and microscopy, compared to their performance in adult cases. Guidelines have introduced molecular tests, including GeneXpert MTB/RIF and GeneXpert MTB/RIF Ultra. These tests use a real-time polymerase chain reaction method and provide information on M. tuberculosis det Read More
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Primary Renal Neuroblastoma: A Case Report and Review of the Literature
Authors: Rejin Kebudi, Dilşad Koca and Ulku Miray YildirimAvailable online: 02 January 2025More LessIntroduction Neuroblastoma is the most common extracranial solid tumor found in childhood. Case Representation Primary renal neuroblastoma has been reported in the literature as case reports. Almost all cases had a preliminary diagnosis of Wilms tumor and were diagnosed as neuroblastoma after nephrectomy. Renal localized neuroblastoma may not be distinguished radiologically from Wilms tumor. Discussion Read More
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Cardiology Consult for the General Pediatrician after Cardiac Manifestations from a SARS-CoV-2 Infection
Available online: 02 October 2024More LessThe novel Coronavirus Disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, created a need for evidence-based guidelines for the evaluation, management, and follow-up after infection. Data have become rapidly available, creating a challenge for medical providers to stay abreast of the ever-evolving recommendations. This document, written collaboratively by pediatric cardiovascular experts, pediatricians, and sports m Read More
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