Coronaviruses - Volume 3, Issue 6, 2022

Background: Novel coronavirus pneumonia COVID-19 has become a serious threat to human health. Traditional Chinese Medicine (TCM) has a good clinical effect in the treatment of COVID-19, with a high effective rate and a low rate of turning to the serious stage. Objective: We generated the web-accessed anti-COVID-19 TCM database to provide the anti-COVID-19 TCM information to develop effective drugs for the treatment Read More

Fruit, vegetables, and green tea contain quercetin (a flavonoid). Some of the diet's most significant sources of quercetin are apples, onions, tomatoes, broccoli, and green tea. Antioxidant, anticancer, anti-inflammatory, antimicrobial, antibacterial, and anti-viral effects have been studied of quercetin. The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus, ribonucleic acid (RNA) polymerase, and other es Read More

The new COVID-19 presents some comorbidities, such as obesity, Alzheimer’s, and coronary risk, among others. We argue that the current understanding of some of these clinical conditions may illuminate the design of future COVID-19 studies to account for a bias that may be the cause of the paradoxical associations between COVID-19 mortality and cytokine storm. Given that we know some of the genetic mecha Read More

Mucormycosis, commonly known as black fungus, is a life-threatening fungal infection belonging to the order Mucorales. It affects individuals with an impaired immune response or immune disorders such as diabetes mellitus, induced immunosuppression, hematological cancers, acquired immune deficiency syndrome, or who have undergone organ transplantation. The symptoms of black fungus include difficulty in breathi Read More

Background: The multitargeted computational approach for the design of drugs to treat severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lung infection from herbal sources may lead to compound(s) that is/are safe (derived from natural sources), effective (act on predefined targets) and broad spectrum (active in both, adult and juvenile population). Objective: The present work aims at developing a specific an Read More

Background: The Omicron variant B.1.1.529 has led to a new dynamic in the COVID-19 pandemic, with an increase in cases worldwide. Its rapid propagation favors the emergence of novel sublineages, including BA.4 and BA.5. The latter has shown increased transmissibility compared to other Omicron sub-lineages. In Senegal, the emergence of the Omicron variant in December 2021 characterized the triggering of a sho Read More