Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Coronaviruses
  4. Fast Track Articles
  5. Fast Track Article
image of Investigating the Relationship Between the Levels of Hematological and Biochemical Parameters of COVID-19 Patients with the Length of Hospitalization

Abstract

Background

Identifying and treating patients with COVID-19 requires the use of quick and precise laboratory diagnostic techniques that assess the patient's health and identify the illness..

Aim

This study was conducted to determine the relationship between hematological and biochemical parameters and length of hospitalization in patients with COVID-19.

Methods

This is a cross-sectional study of a descriptive-analytical type, which was conducted by census method on 360 medical records of patients with COVID-19 in Imam Khomeini Hospital in Jiroft in 2022. Data were analyzed using descriptive and inferential statistics tests.

Results

The average number of days of hospitalization in the present study was 4 days. The rate of COVID-19 was higher in men than in women. The most common underlying diseases in the patients were heart, pulmonary, and diabetes. Among the biochemical parameters, only lactate dehydrogenase (LDH), blood urea nitrogen (BUN), aspartate aminotransferase (AST), alanine transaminase (ALT), platelet (PLT), and erythrocyte sedimentation rate (ESR) parameters had a statistically significant relationship with the total length of hospitalization (-value<0.001). LDH, AST, ALT, creatinine (Cr), creatine phosphokinase (CPK), blood sugar (BS), total bilirubin, and direct bilirubin parameters were higher than normal in hospitalized patients.

Conclusion

The results showed that there is a relationship between LDH, BUN, AST, ALT, PLT, and ESR parameters and the length of hospitalization of patients. The levels of LDH, AST, ALT, Cr, CPK, BS, total bilirubin, and direct bilirubin parameters in patients were higher than normal.

© 2024 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/covid/10.2174/0126667975328744241122041401
2024-12-03
2025-01-31

  • From This Site

    /content/journals/covid/10.2174/0126667975328744241122041401
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. Bittar C. Machado R.R.G. Comelis M.T. Bueno L.M. Beguelini M.R. Morielle-Versute E. Nogueira M.L. Rahal P. Alphacoronavirus detection in lungs, liver, and intestines of bats from Brazil. Microb. Ecol. 2020 79 1 203 212 10.1007/s00248‑019‑01391‑x 31144002
    [Google Scholar]
  2. Sungsuwan S. Jongkaewwattana A. Jaru-Ampornpan P. Nucleocapsid proteins from other swine enteric coronaviruses differentially modulate PEDV replication. Virology 2020 540 45 56 10.1016/j.virol.2019.11.007 31756532
    [Google Scholar]
  3. Ghaffari Darab M. Keshavarz K. Sadeghi E. Shahmohamadi J. Kavosi Z. The economic burden of coronavirus disease 2019 (COVID-19): evidence from Iran. BMC Health Serv. Res. 2021 21 1 132 10.1186/s12913‑021‑06126‑8 33573650
    [Google Scholar]
  4. Mirzaei A. Raesi R. Saghari S. Raei M. Evaluation of family caregiver burden among COVID-19 patients. Open Public Health J. 2020 13 1 808 814 10.2174/1874944502013010808
    [Google Scholar]
  5. Ashour H.M. Elkhatib W.F. Rahman M.M. Elshabrawy H.A. Insights into the recent 2019 novel coronavirus (SARS-CoV-2) in light of past human coronavirus outbreaks. Pathogens 2020 9 3 186 10.3390/pathogens9030186 32143502
    [Google Scholar]
  6. Sharma A. Ahmad Farouk I. Lal S.K. COVID-19: a review on the novel coronavirus disease evolution, transmission, detection, control and prevention. Viruses 2021 13 2 202 10.3390/v13020202 33572857
    [Google Scholar]
  7. Raesi R. Abbasi Z. Bokaie S. Raei M. Hushmandi K. Investigation of the relationship between work-family conflict and the quality of nursing care among nurses working in the Covid-19 ward. EBNESINA 2022 23 4 33 43
    [Google Scholar]
  8. Zu Z.Y. Jiang M.D. Xu P.P. Chen W. Ni Q.Q. Lu G.M. Zhang L.J. Coronavirus disease 2019 (COVID-19): a perspective from China. Radiology 2020 296 2 E15 E25 10.1148/radiol.2020200490 32083985
    [Google Scholar]
  9. Backer J.A. Klinkenberg D. Wallinga J. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20–28 January 2020. Euro Surveill. 2020 25 5 2000062 10.2807/1560‑7917.ES.2020.25.5.2000062 32046819
    [Google Scholar]
  10. Raesi R. Abbasi Z. Raei M. Hushmandi K. The relationship between the incidence of COVID-19 with the underlying diseases in hospitalized patients. EBNESINA 2022 24 3 75 80
    [Google Scholar]
  11. Çalıca Utku A. Budak G. Karabay O. Güçlü E. Okan H.D. Vatan A. Main symptoms in patients presenting in the COVID-19 period. Scott. Med. J. 2020 65 4 127 132 10.1177/0036933020949253 32807018
    [Google Scholar]
  12. Alimohamadi Y. Sepandi M. Taghdir M. Hosamirudsari H. Determine the most common clinical symptoms in COVID-19 patients: a systematic review and meta-analysis. J. Prev. Med. Hyg. 2020 61 3 E304 E312 33150219
    [Google Scholar]
  13. Raesi R. Abbasi Z. Saghari S. Varzeghani M.H.M. Gholami M.H. Mirzaei S. Assessment of health literacy and self-care behaviors among patients discharged from covid-19 wards. Archives of Advances in Biosciences. 2022 13 2 1 9
    [Google Scholar]
  14. Zhang J. Dong X. Cao Y. Yuan Y. Yang Y. Yan Y. Akdis C.A. Gao Y. Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China. Allergy 2020 75 7 1730 1741 10.1111/all.14238 32077115
    [Google Scholar]
  15. Abbasi Z. Moghadaci A. Mohammadnahal L. Sangrizeh F.H. Gholami M.H. Baeelashaki R. Hushmandi K. Raesi R. Khalilipour A. Dashti S. Investigating how Interleukin 6 Serum Level, Blood Group Type, and Underlying Diseases are Associated in Patients Admitted to the COVID-19 Intensive Care Unit: A Retrospective Study. Open Public Health J. 2023 16 1 e187494452309191 10.2174/0118749445258188230922115257
    [Google Scholar]
  16. Moghadaci A. Saghari S. Abbasi Z. Zandieh M.A. Gholami M.H. Hushmandi K. Rudi A.M. Raesi R. A Study of how the Serum Levels of Inflammatory Markers Correlate with Hemoglobin Oxygen Saturation Percentage and the Type of Respiratory Support Received by Covid-19 Patients Hospitalized in Intensive Care Units. Open Public Health J. 2024 17 1 e18749445260299 10.2174/0118749445260299231205041315
    [Google Scholar]
  17. Chang D. Lin M. Wei L. Xie L. Zhu G. Dela Cruz C.S. Sharma L. Epidemiologic and clinical characteristics of novel coronavirus infections involving 13 patients outside Wuhan, China. JAMA 2020 323 11 1092 1093 10.1001/jama.2020.1623 32031568
    [Google Scholar]
  18. Blumfield E. Levin T.L. COVID-19 in pediatric patients: a case series from the Bronx, NY. Pediatr. Radiol. 2020 50 10 1369 1374 10.1007/s00247‑020‑04782‑2 32728901
    [Google Scholar]
  19. Zhu B. Feng X. Jiang C. Mi S. Yang L. Zhao Z. Zhang Y. Zhang L. Correlation between white blood cell count at admission and mortality in COVID-19 patients: a retrospective study. BMC Infect. Dis. 2021 21 1 574 10.1186/s12879‑021‑06277‑3 34126954
    [Google Scholar]
  20. Rodriguez-Morales A.J. Cardona-Ospina J.A. Gutiérrez-Ocampo E. Villamizar-Peña R. Holguin-Rivera Y. Escalera-Antezana J.P. Alvarado-Arnez L.E. Bonilla-Aldana D.K. Franco-Paredes C. Henao-Martinez A.F. Paniz-Mondolfi A. Lagos-Grisales G.J. Ramírez-Vallejo E. Suárez J.A. Zambrano L.I. Villamil-Gómez W.E. Balbin-Ramon G.J. Rabaan A.A. Harapan H. Dhama K. Nishiura H. Kataoka H. Ahmad T. Sah R. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Med. Infect. Dis. 2020 34 101623 10.1016/j.tmaid.2020.101623 32179124
    [Google Scholar]
  21. Yang Y. Peng F. Wang R. Guan K. Jiang T. Xu G. Sun J. Chang C. Chang C. The deadly coronaviruses: The 2003 SARS pandemic and the 2020 novel coronavirus epidemic in China. J. Autoimmun. 2020 109 102434 10.1016/j.jaut.2020.102434 32143990
    [Google Scholar]
  22. Wang D Hu B Hu C Zhu F Liu X Zhang J Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. 2020 323 11 1061 9
    [Google Scholar]
  23. Chen H. Guo J. Wang C. Luo F. Yu X. Zhang W. Li J. Zhao D. Xu D. Gong Q. Liao J. Yang H. Hou W. Zhang Y. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet 2020 395 10226 809 815 10.1016/S0140‑6736(20)30360‑3 32151335
    [Google Scholar]
  24. Liu L. Lei X. Xiao X. Yang J. Li J. Ji M. Du W. Tan H. Zhu J. Li B. Jin Z. Liu W. Wu J. Liu Z. Epidemiological and clinical characteristics of patients with coronavirus disease-2019 in Shiyan City, China. Front. Cell. Infect. Microbiol. 2020 10 284 10.3389/fcimb.2020.00284 32574282
    [Google Scholar]
  25. Liu D. Li L. Wu X. Zheng D. Wang J. Yang L. Zheng C. Pregnancy and perinatal outcomes of women with coronavirus disease (COVID-19) pneumonia: a preliminary analysis. AJR Am. J. Roentgenol. 2020 215 1 127 132 10.2214/AJR.20.23072 32186894
    [Google Scholar]
  26. Blitz MJ Rochelson B Minkoff H Meirowitz N Prasannan L London V Maternal mortality among women with coronavirus disease 2019 admitted to the intensive care unit. Am J Obstet Gynecol. 2020 223 4 595 599 10.1016/j.ajog.2020.06.020
    [Google Scholar]
  27. Bahl P. Doolan C. de Silva C. Chughtai A.A. Bourouiba L. MacIntyre C.R. Airborne or droplet precautions for health workers treating coronavirus disease 2019? J. Infect. Dis. 2022 225 9 1561 1568 10.1093/infdis/jiaa189 32301491
    [Google Scholar]
  28. Linton N. Kobayashi T. Yang Y. Hayashi K. Akhmetzhanov A. Jung S. Yuan B. Kinoshita R. Nishiura H. Incubation period and other epidemiological characteristics of 2019 novel coronavirus infections with right truncation: a statistical analysis of publicly available case data. J. Clin. Med. 2020 9 2 538 10.3390/jcm9020538 32079150
    [Google Scholar]
  29. Wu Z McGoogan JM Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020 323 13 1239 42
    [Google Scholar]
  30. Huang C. Wang Y. Li X. Ren L. Zhao J. Hu Y. Zhang L. Fan G. Xu J. Gu X. Cheng Z. Yu T. Xia J. Wei Y. Wu W. Xie X. Yin W. Li H. Liu M. Xiao Y. Gao H. Guo L. Xie J. Wang G. Jiang R. Gao Z. Jin Q. Wang J. Cao B. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020 395 10223 497 506 10.1016/S0140‑6736(20)30183‑5 31986264
    [Google Scholar]
  31. Zayet S. Gendrin V. Klopfenstein T. Natural history of COVID-19: Back to basics. New Microbes New Infect. 2020 38 100815 10.1016/j.nmni.2020.100815 33204429
    [Google Scholar]
  32. Rothan H.A. Byrareddy S.N. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J. Autoimmun. 2020 109 102433 10.1016/j.jaut.2020.102433 32113704
    [Google Scholar]
  33. Guan W-Y. Ni Z-Y. Hu Y. Liang W-H. Ou C-Q. He J-X. Clinical characteristics of 2019 novel coronavirus infection in China. MedRxiv 2020 2020 20020974 10.1101/2020.02.06.20020974
    [Google Scholar]
  34. Liu K. Chen Y. Lin R. Han K. Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients. J. Infect. 2020 80 6 e14 e18 10.1016/j.jinf.2020.03.005 32171866
    [Google Scholar]
  35. Ghapanvari F. Moradi M. Namdar P. Mirzadeh M. Yekefallah L. Predictors of disease severity and death in patients admitted with COVID-19 in infectious diseases center, Qazvin University of Medical Sciences, Iran: A cross-sectional study. Majallah-i Danishkadah-i Pizishki-i Isfahan 2021 39 629 443 450
    [Google Scholar]
  36. Liu C. Jiang Z-C. Shao C-X. Zhang H-G. Yue H-M. Chen Z-H. Ma B.Y. Liu W.Y. Huang H.H. Yang J. Wang Y. Liu H.Y. Xu D. Wang J.T. Yang J.Y. Pan H.Q. Zou S.Q. Li F.J. Lei J.Q. Li X. He Q. Gu Y. Qi X.L. [Preliminary study of the relationship between novel coronavirus pneumonia and liver function damage: a multicenter study]. Zhonghua Gan Zang Bing Za Zhi 2020 28 2 107 111 32077660
    [Google Scholar]
  37. Lu H. Ai J. Shen Y. Li Y. Li T. Zhou X. A descriptive study of the impact of diseases control and prevention on the epidemics dynamics and clinical features of SARS-CoV-2 outbreak in Shanghai, lessons learned for metropolis epidemics prevention. MedRxiv 2020 2020 20025031 10.1101/2020.02.19.20025031
    [Google Scholar]
  38. Cai Q. Huang D. Ou P. Yu H. Zhu Z. Xia Z. Su Y. Ma Z. Zhang Y. Li Z. He Q. Liu L. Fu Y. Chen J. COVID‐19 in a designated infectious diseases hospital outside Hubei Province, China. Allergy 2020 75 7 1742 1752 10.1111/all.14309 32239761
    [Google Scholar]
  39. Gozidehkar Z. Gahani H. Davary A. Borna H. Prevalence and parameters related to infection and mortality due to COVID-19 among patients of Shohada Ghaen Hospital, Ghaen, Iran, 2020. J Birjand Univ Med Sci. 2021 28 4 375 384
    [Google Scholar]
  40. Chen X.Y. Huang M.Y. Xiao Z. Yang S. Chen X.Q. Lactate dehydrogenase elevations is associated with severity of COVID-19: a meta-analysis. Crit. Care 2020 24 1 459 10.1186/s13054‑020‑03161‑5 32709251
    [Google Scholar]
  41. Sawalha K. Abozenah M. Kadado A.J. Battisha A. Al-Akchar M. Salerno C. Hernandez-Montfort J. Islam A.M. Systematic review of COVID-19 related myocarditis: insights on management and outcome. Cardiovasc. Revasc. Med. 2021 23 107 113 10.1016/j.carrev.2020.08.028 32847728
    [Google Scholar]
  42. Song F. Shi N. Shan F. Zhang Z. Shen J. Lu H. Ling Y. Jiang Y. Shi Y. Emerging 2019 novel coronavirus (2019-nCoV) pneumonia. Radiology 2020 295 1 210 217 10.1148/radiol.2020200274 32027573
    [Google Scholar]
/content/journals/covid/10.2174/0126667975328744241122041401
Loading
Investigating the Relationship Between the Levels of Hematological and Biochemical Parameters of COVID-19 Patients with the Length of Hospitalization
Bentham Science Publishers ; https://doi.org/10.2174/0126667975328744241122041401
/content/journals/covid/10.2174/0126667975328744241122041401
/content/journals/covid/10.2174/0126667975328744241122041401
Loading

Data & Media loading...


  • Article Type:     Research Article
Keywords: COVID-19 ; biochemical parameters ; hospitalization ; biomarker ; patient ; Hematological parameters ; test ; hospital
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test