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2000
Volume 7, Issue 2
  • ISSN: 2666-7967
  • E-ISSN: 2666-7975

Abstract

Introduction

In the face of the rise of COVID-19, the multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 has been reported, and an increase in MIS-C cases has been observed throughout the world. The majority of these cases were similar to Kawasaki disease concerning clinical presentation.

Case Presentation

Despite similarities, MIS-C cases present clinical and laboratory differentiation, which makes it essential to portray similar cases worldwide to have a better consensus in the future. A 7-year-old male child visited the hospital with the chief complaints of fever associated with chills, rigors, and excessive myalgia for 3 days. He had a history of elevated high C-reactive protein (CRP) of 42.7 mg/L. He was diagnosed with Paediatric inflammatory multisystem syndrome (PIMS)-grade 3. Here, for the first time, we bring an Indian MIS-C case with COVID-19-associated Paediatric inflammatory multisystem syndrome (PIMS)-grade 3.

Conclusion

PIMS-TS infection in paediatrics is associated with a wider range of complications, and the importance of musculoskeletal complications in PIMS-TS has been discussed.

© 2026 Bentham Science Publishers
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2024-10-08
2026-02-20

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References

  1. RaoG.S.N.K. GowthamiB. NaveenN.R. SamudralaP.K. An updated review on potential therapeutic drug candidates, vaccines and an insight on patents filed for COVID-19.Curr. Res. Pharmacol. Drug Discov.2021210006310.1016/j.crphar.2021.100063 34870158
     [Google Scholar]
  2. NakraN. BlumbergD. Herrera-GuerraA. LakshminrusimhaS. Multi-system inflammatory syndrome in children (MIS-C) following SARS-CoV-2 infection: Review of clinical presentation, hypothetical pathogenesis, and proposed management.Children (Basel)2020776910.3390/children7070069 32630212
     [Google Scholar]
  3. LokeY.H. BerulC.I. HarahshehA.S. Multisystem inflammatory syndrome in children: Is there a linkage to kawasaki disease?Trends Cardiovasc. Med.202030738939610.1016/j.tcm.2020.07.004 32702413
     [Google Scholar]
  4. AbramsJ.Y. Godfred-CatoS.E. OsterM.E. Multisystem inflammatory syndrome in children associated with severe acute respiratory syndrome coronavirus 2: A systematic review.J. Pediatr.20202264554.e110.1016/j.jpeds.2020.08.003 32768466
     [Google Scholar]
  5. McCrindleB.W. RowleyA.H. NewburgerJ.W. Diagnosis, treatment, and long-term management of kawasaki disease: A scientific statement for health professionals from the american heart association.Circulation201713517e927e99910.1161/CIR.0000000000000484 28356445
     [Google Scholar]
  6. Singh-GrewalD. LucasR. MacartneyK. Update on the COVID‐19‐associated inflammatory syndrome in children and adolescents; paediatric inflammatory multisystem syndrome‐temporally associated with SARS‐CoV‐2.J. Paediatr. Child Health20205681173117710.1111/jpc.15049 32735721
     [Google Scholar]
  7. WhittakerE. BamfordA. KennyJ. Clinical characteristics of 58 children with a pediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2.JAMA2020324325926910.1001/jama.2020.10369 32511692
     [Google Scholar]
  8. Opoka-WiniarskaV. GrywalskaE. RolińskiJ. PIMS-TS, the new paediatric systemic inflammatory disease related to previous exposure to SARS-CoV-2 Infection—“Rheumatic Fever” of the 21st Century?Int. J. Mol. Sci.2021229448810.3390/ijms22094488
     [Google Scholar]
  9. Fernández-SarmientoJ. De SouzaD. JaborniskyR. GonzalezG.A. Arias LópezM.P. PalacioG. Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): a narrative review and the viewpoint of the Latin American Society of Pediatric Intensive Care (SLACIP) Sepsis Committee.BMJ Paediatr. Open202151e00089410.1136/bmjpo‑2020‑000894 34192188
     [Google Scholar]
  10. LacinaL. BrábekJ. FingerhutováŠ. ZemanJ. SmetanaK.Jr Pediatric Inflammatory Multisystem Syndrome (PIMS) – Potential role for cytokines such Is IL-6.Physiol. Res.202170215315910.33549/physiolres.934673 33992044
     [Google Scholar]
  11. VenkataramanA. KumarN.P. Plasma biomarker profiling of PIMS-TS, COVID-19 and SARS-CoV-2 seropositive children - A cross-sectional observational study from southern India.EBioMedicine20216610331710.1016/j.ebiom.2021.103317
     [Google Scholar]
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Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with COVID-19-PIMS-grade 3: A Case Report
Coronaviruses 7, E26667975327652 (2026); https://doi.org/10.2174/0126667975327652240925113837
/content/journals/covid/10.2174/0126667975327652240925113837
/content/journals/covid/10.2174/0126667975327652240925113837
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  • Article Type:     Case Report
Keyword(s): C-reactive protein; coronavirus; COVID-19; kawasaki disease; multisystem inflammatory syndrome in children; paediatric inflammatory multisystem syndrome

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