Current Organic Synthesis - Volume 18, Issue 1, 2021

Background: Pyranoid spirofused sugar derivatives represent a class of compounds with a significant impact in the literature. From the structural point of view, the rigidity inferred by the spirofused entity has made these compounds object of interest mainly as enzymatic inhibitors, in particular, carbohydrate processing enzymes. Among them glycogen phosphorylase and sodium glucose co-transporter 2 are important Read More

The implementation of heterogeneous photo-nanocatalysts in organic syntheses has been investigated greatly in the last decade as a result of the increasing demand to achieve the organic reactions via the use of green approaches and through the availability of visible light source. Herein, the presented results describe the basic concepts and state-of-the-art of fundamental insight into key features that influence the catalytic p Read More

Background: Isatin (IST) is a crucial pharmacologically active compound, chemically known as indole- 1H-2,3-dione. Development of different IST based analogues acquired significant awareness because of its pronounced therapeutic importance such as analgesic, anticancer, anti-inflammatory, antitubercular, antimicrobial, antifungal, antiviral (effective against SARS coronavirus 3C protease) and many other activit Read More

Background: The reactivity of 4-(dicyanomethylene)-3-methyl-l-phenyl-2-pyrazoline-5-one DCNP 1 and its derivatives makes it valuable as a building block for the synthesis of heterocyclic compounds like pyrazolo- imidazoles, -thiazoles, spiropyridines, spiropyrroles, spiropyrans, and others. As a number of publications have reported on the reactivity of DCNP and its derivatives, we compiled some features of this interesting molec Read More

;Introduction: NiFe2O4@SiO2nPr@glucose catalyzed synthesis of novel 5-pyrazolin-1,2,4-triazazolidine- 3-ones (thiones). Materials and Methods: Amino glucose-functionalized silica-coated NiFe2O4 nanoparticles (NiFe2O4@SiO2 nPr@glucose amine or NiFe2O4@SiP@GA) were synthesized and characterized by X-ray powder diffraction (XRD), X-ray spectroscopy (EDX), transmission electron microscope (TEM), field emission scan Read More