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- ISSN: 1570-1794
- E-ISSN: 1875-6271
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Natural Naphthoquinones with Great Importance in Medicinal Chemistry
- Source: Current Organic Synthesis, Volume 13, Issue 3, Jun 2016, p. 334 - 371
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- 01 Jun 2016
Abstract
This review involves the chemistry and biochemistry of lapachol, β-lapachone and lawsone, examples of bioactive natural products that still being under biological evaluation and stimulated several research groups to prepare derivatives and analogues and test them against several anticancer, trypanocidal, antinflammatory, tuberculostatic, and antimalarial targets, as well as other parasitology targets related to important infectious diseases.
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