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- ISSN: 1570-1794
- E-ISSN: 1875-6271
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One-pot Approach to 4-Vinyl-1,2,3-Triazoles by Cycloaddition of Azides with Propargyl Alcohols Catalyzed by Cu(I)/Ru(III)/TFA
- Source: Current Organic Synthesis, Volume 9, Issue 6, Dec 2012, p. 898 - 902
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- 01 Dec 2012
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Abstract
An efficient and regioselective one-pot direct synthesis of 4-vinyl-1,2,3-triazoles via cycloaddition of azides with propargyl alcohols and dehydration catalyzed by a CuCl/RuCl3.3H2O bimetallic catalysts in the presence of TFA (Trifluoroacetic acid) is developed.
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