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oa Editorial [ Hot Topic:Organic Synthesis Using Green Reaction Media (Guest Editors: Devdutt Chaturvedi and Nabin C. Barua)]
- Source: Current Organic Synthesis, Volume 9, Issue 1, Feb 2012, p. 1 - 1
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- 01 Feb 2012
Abstract
Synthesis of organic compounds through a series of synthetic steps involves use of a variety of organic chemicals/solvents which are harmful either directly or indirectly. In recent years, water and ionic liquids have emerged as powerful green reaction media for various organic transformations and are frequently employed in organic synthesis affording excellent yields of the desired products. Several researchers in recent time have reviewed the role of water and ionic liquids from time to time. The present hot topic issue will give an overview of the role of these green solvents in the synthesis of diverse compounds under mild reaction conditions. This hot topic issue contains seven review articles authored by scientists from different parts of the world, highlighting the role of ionic liquids/water on the various chemical reactions. I. Fabio Marinelli reviewed a variety of copper mediated organic transformations in water, covering arylation of nucleophiles, alkyne coupling, dipolar cycloadditions, Diels-Alder reactions, oxidations, condensations and enantioselective reactions. II. We have reviewed the recent developments on the role of water in the variety of C-C bond forming reactions such as Sonogashira, Suzuki, Heck, Stille coupling reactions and metathesis reaction and synthesis of some interesting heterocycles using C-C bond forming reactions. III. Franca Bigi and Carla Quarantelli have reviewed the various kinds of Knoevanagel condensations in water, dealing with an exhaustive outcome on this reaction…..