Current Organocatalysis - Volume 9, Issue 2, 2022

The supported ionic liquid (SIL) membranes have demonstrated huge potential for numerous applications in current separation science and catalysis. Membrane technology allows for the separation of complex mixtures of gases, vapors, liquids and /or solids below trivial conditions. Simultaneous chemical transformations can also be achieved in membranes by using catalytically active materials comprising the mem Read More

Aim and Objective: In this work, we have prepared two bis-dicationic ionic liquids with the same cationic core (Bis-imidazole) and different counter-anions using sulfuric acid and perchloric acids. After that, the efficiency and ability of these compounds as catalysts were investigated and compared with respect to the promotion of Knoevenagel condensation and synthesis of benzo[ b] pyran derivatives to see the effect of t Read More

An efficient and green method for the Friedländer quinoline synthesis has been described. The synthesis was performed under microwave irradiation using ionic liquid [Bmim]HSO4 as a catalyst. A diverse range of quinoline derivatives was obtained in high yields from 2-aminoaryl aldehydes and ketones under solvent-free conditions.

The use of proline-based organocatalysts has acquired significant attention in organic synthesis, especially in enantioselective synthesis. Proline and its derivatives are proven to be quite effective chiral organocatalysts for a variety of transformations, including the aldol reaction, which is considered as one of the important C-C bond forming reactions in organic synthesis. The use of chiral organocatalysts has several adva Read More

Background: Baylis-Hillman reaction requires cheap starting materials, easy reaction protocol, and possibility to create the chiral center in the reaction product has increased the synthetic efficacy of this reaction which also suffers from high catalyst loading, low reaction rate, and poor yield. Objective: The extensive use of various functional or non-functional ionic liquids (ILs) with organocatalyst acts not only as reaction mediu Read More

Aim: The objective of the work is to synthesize, characterize and biochemically analyze Azo-metal complex of Embelin with Second Group Transition Metals. Background: The genus Embelia is a well-known herb and has considerable importance in the field of pharmaceutical chemistry. The plant species has been used considerably as a traditional medicine in Ayurveda, old Chinese medicine, and Siddha for a long time. The dried b Read More

Background: Polycarboxylic acids are of interest as simple mimics for cellulase enzyme- catalyzed depolymerization of cellulose. In this study, DFT calculations were used to investigate the effect of structure on dicarboxylic acid organo-catalyzed hydrolysis of cellulose model compound D-cellobiose to D-glucose. Methods: Binding energy of the complex formed between D-cellobiose and acid (Ebind), as well as glycosidic oxy Read More

Aim: Here, we have reported easy one-pot access to a series of oxazolines using a modified Castro-Stephens coupling protocol. Background: 2-oxazolines have been shown to have significant biological activity and wide-ranging applications in organic chemistry. These properties make oxazolines as heterocyclic compounds of immense importance. Objective: The objective of this study is to synthesize oxazoline derivativ Read More

Background: The present work describes an eco-friendly and sustainable approach for the Knoevenagel condensation of an aromatic aldehyde with ethyl cyanoacetate, and salicylaldehyde with Meldrum acid for the synthesis of ethyl benzylidenecyanoacetate and 3-carboxy coumarin (2-oxo-2H-1-benzopyran) derivatives, respectively. The reaction was performed under green catalytic media-Water Extract of Watermelon Fruit Pe Read More

Objective: Microwave technology, together with enzymatic catalysis, is a nature-friendly chemical synthesis method with low wastage of solvent and a good yield of the products. Methods: Enzymes from various microorganisms can be used in the biochemical processes of a wide range of compounds assisted by microwave irradiation. Results: In this work, the microwave-induced reaction of α-keto β-lactams by Baker's yeas Read More