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Volume 12, Issue 1
  • ISSN: 2213-3372
  • E-ISSN: 2213-3380

Abstract

Introduction

Synthesis of NiO nanoparticles using environmentally friendly Pongamia pinnata seeds as a source of fuel was demonstrated using a solution combustion approach.

Methods

The protocol for the synthesis of NiO NPs is simple and efficient. NiO NPs were utilized as the catalyst for the synthesis of -protected aminoalkyl sulfides from -protected alkyl thiols and bromo esters of amino acids.

Results

The NiO NPs were characterized using XRD, SEM, and EDX techniques. -protected aminoalkyl sulfides were characterized by HRMS, 1H, and 13C NMR techniques and were evaluated for their antifungal activities, against using Fluconazole as a standard.

Conclusion

The current study presents an effective approach for synthesizing a new class of sulfides from -protected aminoalkyl thiols and bromomethyl esters in the presence of nano NiO as a catalyst.

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2024-06-03
2025-04-09

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Green Synthesis of NiO Nanoparticles using Pongamia pinnata and their Catalytic Utility in the Synthesis of N-Fmoc/Cbz-protected Amino Acid Derived Sulfides and their Biological Investigations
Curr. Organocatal. 12, 26 (2025); https://doi.org/10.2174/0122133372305191240528115104
/content/journals/cocat/10.2174/0122133372305191240528115104
/content/journals/cocat/10.2174/0122133372305191240528115104
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  • Article Type:     Research Article
Keyword(s): antifungal activity; C-S bond-formation; NiO catalysis; Peptidomimetics; Pongamia pinnata; solution combustion synthesis; sulfides; thiols

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