Current Organic Chemistry - Volume 28, Issue 7, 2024

Among the several peroxides available, meta-chloroperbenzoic acid (mCPBA) plays an efficient role of oxidizing reagent and is used for many oxidative transformations, such as oxidation of various functional groups, carbon-carbon, carbon-hetero bond formation, heterocyclic ring formation, heteroarylation, oxidative cross-coupling, lactonization, oxidative dearomatization, α-oxytosylation or α-acetoxylation, oxidati Read More

3D bioprinting is a novel technology that has gained significant attention recently due to its potential applications in developing simultaneously controlled drug delivery systems (DDSs) for administering several active substances, such as growth factors, proteins, and drug molecules. This technology provides high reproducibility and precise control over the fabricated constructs in an automated way. Chitosan is a natural-d Read More

During the last two decades, non-conventional solvents, especially various ionic liquids, have been utilized as efficient reaction media as they can play a dual role as solvents and promoters. The use of ionic liquids as a medium increases the efficiency of the reactions due to their inherent features like high thermal stability, ability to act as a catalyst, non-volatility, high polarity, reusability, ability to dissolve a large number of Read More

The quinoline derivatives arouse interest due to their broad spectrum of activity. The phosphorus compounds under investigation, quinolinylphosphonic and -phosphinic acids and aminophenylphosphonic and -phosphinic acids, possess potent bioactive properties, mimicking amino acids, phosphate esters, anhydrides, or carboxylate groups in enzymes. Despite its potential value, there is no reported example Read More

Sulfonamide, imidazole, and triazole chemical nuclei possess good antimicrobial potential. This study aimed to amalgamate sulfonamide, imidazole, and triazole moieties in a single molecular framework with the intent of improving their antimicrobial activities. The objective of this study was the synthesis of conjugates containing sulfonamide and azole moieties along with in vitro and in silico evaluation as antimicrobial candidates Read More