Current Organic Chemistry - Volume 28, Issue 1, 2024

Sustainable production of biofuels from lignocellulosic biomass (LBM) is considered one of the promising solutions to solve the current energy crisis caused by overreliance on fossil fuels. Enzymatic hydrolysis is a crucial step in determining the efficient conversion of biomass cellulose into biofuels as well as high value-added chemicals, and it has the characteristics of efficient reaction, economy, and environmental friendlin Read More

Phenylquinoline-4-carboxylic acid derivatives have garnered significant attention in recent years due to their diverse pharmacological and industrial applications. This comprehensive review summarizes the latest advancements in the synthesis and diverse range of applications of phenylquinoline-4-carboxylic acid derivatives. This review provides a brief overview of the significance of phenylquinoline-4-carboxylic acid derivatives in Read More

In recent years, perovskite solar cells, which use a hybrid inorganic-organic material, have also made remarkable progress and achieved a rapid increase in efficiency. The organic materials used are usually small conductive molecules, polymers or oligomers. The fused thiophenes, polythiophenes and olithiophenes used for this purpose are presented. The condensed thiophene-based small molecule for DSSCs shows Read More

The present article reports the synthesis, characterization, and antioxidant activity of the chalcone-deoxycholic acid conjugates. The structures of the synthesised bile acidchalcone conjugates have been determined using 1H and 13C NMR spectroscopy. According to the results of the DPPH experiment, compounds 5e (3, 4, 5-methoxy; IC50; 15.04 μg /ml) and 5f (4-hydroxy group; IC50; 11.73 μg /ml) had higher antioxidant ac Read More

A convenient synthesis of polyalkoxy-1,4-naphthoquinones, good starting materials for analogues of natural quinones, has been developed. Bromonaphthoquinone, more stable than its hydroxylated analogue, turned out to be a convenient and accessible key synthon for the preparation of various polyalkoxylated naphthoquinones. The obtained quinones could be useful starting materials for the preparation of biologically Read More

This study aimed to prepare and characterize chitosan nanoparticles encapsulating a nicotinamide derivative (Ni-CS-NP). Additionally, the therapeutic effectiveness, cytotoxicity, selectivity, and immunomodulatory properties of Ni-CS-NP were evaluated in human breast and colon cancer cell lines. Chitosan nanoparticles have shown potential as drug delivery carriers due to their biocompatibility and controlled relea Read More

This research paper embarks on an interdisciplinary exploration encompassing synthetic chemistry, pharmacology, and computational biology. The development of novel anti-inflammatory agents is an imperative endeavor within pharmaceutical research. Pyrimidines and thienopyrimidines are class of heterocyclic compounds that have gained prominence for their diverse pharmacological properties, including potential anti-infla Read More

Diseases caused by bacteria are a big challenge for scientists worldwide. These bacteria can be resistant through the adaption of new ways to protect themselves against antimicrobial drugs and thus become multidrug resistance. In this work, new derivatives of 1,3,4-oxadiazole- cholic acid were synthesized and fully characterized using different techniques, such as 1H-NMR, 13C-NMR, and HRMS. Their biological activity, alon Read More