Current Organic Chemistry - Volume 26, Issue 17, 2022

Aminocoumarins are found to be present in many natural products, pharmaceuticals, and organic materials. These derivatives demonstrate numerous biological activities including DNA gyrase, anti-proliferative and anti-breast cancer activities. Among the allaminocoumarin derivatives, 4-aminocoumarin derivatives have been reported to exhibit anticancer and anti-fungal properties. 4-Aminocoumarins and their derivative Read More

Ruthenium-catalyzed amination reactions have gained much attention in recent times. Due to the low cost and versatile nature of ruthenium, its chemistry is expanding rapidly. The amination reaction provides an efficient pathway to synthesize organonitrogen compounds. These reactions are highly regio- and stereoselective and exhibit wide substrate scope. This review gives an overview of the ruthenium-catalyzed allylic amin Read More

Amino heterocycles are important in drug design due to their unique intrinsic and physicochemical properties. Though these molecules look simple, their selective reduction is challenging because of their rich electron density in the ring. Additionally, reducing nitro groups in heterocycles is crucial in designing different materials. With this in view, several reduction methods have been developed and applied to various heterocyclic c Read More

Green solvent is a topic of increasing attention in modern chemistry because of the consciousness of the effect of solvents on air quality, energy usage, pollution, and continuous climate change. Over the past few years, remarkable progress has been made to accomplish these goals by giving interest in sustainable synthesis. For sustainable development, continuous efforts have been put forward for addressing these issues and Read More

Continuous flow chemistry refers to the delicate chemical production processes, without interruptions and with the best possible use. It is a practice identified as an opportune for the incorporation of the principles of Green Chemistry into economically favorable industrial processes. The purpose of this work is to verify the efficiency advantage and lower the wastage of time and materials that continuous flow extraction can bring t Read More