Current Organic Chemistry - Volume 13, Issue 5, 2009

With this part of the special issue on “Synthetic Organic Chemistry”, inserted in the Volume 13, Number 5, March 2009 of Current Organic Chemistry, my second activity, as Guest Editor, comes to an end. It has indeed been a pleasure to be involved with this work including three reviews which deal with the cycloaddition methodology for biologically active heterocycles, recent developments on rotaxane-based shuttles and Read More

The present review contains a representative sampling from the last 10 years on the synthesis of biologically interesting compounds, prepared by the use of the 1,3-dipolar cycloaddition and Diels-Alder reactions, that have been eventually sequenced into cascade processes to assemble heterocyclic molecules. The important role of click chemistry for the synthesis of bio-inspired compounds have been also outlined.

Artificial molecular machines capable of converting chemical, photochemical and electrochemical energy into mechanical motion represent a high-impact, fast-growing field of interdisciplinary research. These molecular-scale systems utilize a “bottom-up” technology centered upon the design and manipulation of molecular assemblies and are potentially capable of delivering efficient actuation at length scales dramatically smal Read More

Following the previous review of the same title and authors, this up-date deals with the research progress in regeneration of carbonyl compounds from oximes starting from 2001 until today, including some additional deoximation methods appeared during the publication of the previous review. In these years, this topic was dealt together with that of other carbonyl compound derivatives only three times of which one in t Read More

This work presents the main methods of synthesis for [4.n]cyclophanes and reveals the possibilities to use common methods or peculiar ones in order to obtain more efficient access to different cyclophanes which exhibit a four membered bridge. The conformational behavior of [4.n]cyclophanes involving the flexibility of the bridges and the rotational behavior of the aromatic rings is discussed in correlation with t Read More