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Volume 21, Issue 3
  • ISSN: 1573-4013
  • E-ISSN: 2212-3881

Abstract

There are several different categories into which the etiology of pancreatic disease can be subdivided, including inflammation, neoplasia, endocrine dysfunction, and genetic disorders. A comprehensive understanding of the pathogenesis of pancreatitis is necessary for the development of appropriate management methods and therapies, as the disorder has a complicated underlying pathophysiology. Complications such as reduced digestive function, the formation of pseudocysts or abscesses, and ongoing pain are likely as the illness develops. The purpose of this review is to act as a knowledge base. This study aims to examine existing approaches to treating diabetes, including both cutting-edge and tried-and-true therapies. Based on the literature review, the authors discussed how pancreatic failure affected higher animals, explored how the pancreatic exocrine function affects adult and adolescent organism development, and gave an overview of all the conditions that directly affect pancreatic health. There was also a discussion of the link between obesity, lifestyle, nutrition, and pancreatic issues.

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References

  1. KanetoH. NakataniY. MiyatsukaT. MatsuokaT. MatsuhisaM. HoriM. YamasakiY. PDX-1/VP16 fusion protein, together with NeuroD or Ngn3, markedly induces insulin gene transcription and ameliorates glucose tolerance.Diabetes20055441009102210.2337/diabetes.54.4.100915793239
     [Google Scholar]
  2. TakeiY. LoretzCA. The gastrointestinal tract as an endocrine/neuroendocrine/paracrine organ: organization, chemical messengers and physiological targets. In: Fish physiologyAcademic Press2010
     [Google Scholar]
  3. OldfieldL.E. ConnorA.A. GallingerS. Molecular events in the natural history of pancreatic cancer.Trends Cancer20173533634610.1016/j.trecan.2017.04.00528718411
     [Google Scholar]
  4. KellerJ. AghdassiA.A. LerchM.M. MayerleJ.V. LayerP. Tests of pancreatic exocrine function – Clinical significance in pancreatic and non-pancreatic disorders.Best Pract. Res. Clin. Gastroenterol.200923342543910.1016/j.bpg.2009.02.01319505669
     [Google Scholar]
  5. LevittM.D. EckfeldtJ.H. Diagnosis of acute pancreatitis. The Pancreas: Biology, Pathophysiology and Disease.2nd edNYRaven Press1993613635
     [Google Scholar]
  6. VignesvaranK.J. A Study of Etiological Analysis of Acute Pancreatitis and their Outcome in Patients Admitted at Rajiv Gandhi Government General Hospital.Doctoral dissertation, Madras Medical College, Chennai.
     [Google Scholar]
  7. GouldenM.R. The pain of chronic pancreatitis: a persistent clinical challenge.Br. J. Pain20137182210.1177/204946371347923026516493
     [Google Scholar]
  8. LennonA.M. WolfgangC.L. CantoM.I. KleinA.P. HermanJ.M. GogginsM. FishmanE.K. KamelI. WeissM.J. DiazL.A. PapadopoulosN. KinzlerK.W. VogelsteinB. HrubanR.H. The early detection of pancreatic cancer: what will it take to diagnose and treat curable pancreatic neoplasia?Cancer Res.201474133381338910.1158/0008‑5472.CAN‑14‑073424924775
     [Google Scholar]
  9. PowersA.C. D’AlessioD. Endocrine pancreas and pharmacotherapy of diabetes mellitus and hypoglycemia. Goodman and Gilman’s The Pharmacological Basis of Therapeutics.12th ed BruntonL.L. ChabnerB.A. KnollmanB.C. New YorkMcGraw Hill Publishers201112371274
     [Google Scholar]
  10. DhankharS. ChauhanS. MehtaD.K. Nitika SainiK. SainiM. DasR. GuptaS. GautamV. Novel targets for potential therapeutic use in Diabetes mellitus.Diabetol. Metab. Syndr.20231511710.1186/s13098‑023‑00983‑536782201
     [Google Scholar]
  11. RohillaM. Rishabh BansalS. GargA. DhimanS. DhankharS. SainiM. ChauhanS. AlsubaieN. BatihaG.E.S. AlbezrahN.K.A. SinghT.G. Discussing pathologic mechanisms of Diabetic retinopathy & therapeutic potentials of curcumin and β-glucogallin in the management of Diabetic retinopathy.Biomed. Pharmacother.202316911588110.1016/j.biopha.2023.11588137989030
     [Google Scholar]
  12. SharmaP. RaniN. GangwarA. SinghR. KaurR. UpadhyayaK. Diabetic neuropathy: A repercussion of vitamin D deficiency.Curr. Diabetes Rev.2023196e17082220759210.2174/157339981966622081712155135980059
     [Google Scholar]
  13. JoshiS.K. ShresthaS. Diabetes mellitus: A review of its associations with different environmental factors.Kathmandu Univ. Med. J.201082910911521209519
     [Google Scholar]
  14. RaniN. SharmaP. GangwarA. DahiyaR.S. VermaN. Chemical constituents based approach for the management of diabetes.Curr. Diabetes Rev.2023195e22032220250610.2174/157339981866622032209503335319377
     [Google Scholar]
  15. RadhaV. KanthimathiS. AmuthaA. BhavadhariniB. AnjanaR.M. UnnikrishnanR. MohanV. Monogenic diabetes reported in south asians: a systematic review.J. Indian Inst. Sci.2023103130933410.1007/s41745‑023‑00399‑0
     [Google Scholar]
  16. YingH. DeyP. YaoW. KimmelmanA.C. DraettaG.F. MaitraA. DePinhoR.A. Genetics and biology of pancreatic ductal adenocarcinoma.Genes Dev.201630435538510.1101/gad.275776.11526883357
     [Google Scholar]
  17. IlonenJ. LempainenJ. VeijolaR. The heterogeneous pathogenesis of type 1 diabetes mellitus.Nat. Rev. Endocrinol.2019151163565010.1038/s41574‑019‑0254‑y31534209
     [Google Scholar]
  18. BhattamisraS.K. SiangT.C. RongC.Y. AnnanN.C. SeanE.H.Y. XiL.W. LynO.S. ShanL.H. ChoudhuryH. PandeyM. GorainB. Type-3c diabetes mellitus, diabetes of exocrine pancreas-an update.Curr. Diabetes Rev.201915538239410.2174/157339981566619011514570230648511
     [Google Scholar]
  19. RussoP. RandEB. LoomesKM. Diseases of the biliary tree. In: Pathology of pediatric gastrointestinal and liver diseaseBerlin, HeidelbergSpringer201410.1007/978‑3‑642‑54053‑0_10
     [Google Scholar]
  20. DoneleyB. Avian medicine and surgery in practice: companion and aviary birds.CRC press201810.1201/9781315371047
     [Google Scholar]
  21. AbumradN.A. DavidsonN.O. Role of the gut in lipid homeostasis.Physiol. Rev.20129231061108510.1152/physrev.00019.201122811425
     [Google Scholar]
  22. MukherjeeS. The emperor of all maladies: A biography of cancer.Simon and Schuster2010
     [Google Scholar]
  23. PradoC.L. Pugh-BernardA.E. ElghaziL. Sosa-PinedaB. SusselL. Ghrelin cells replace insulin-producing β cells in two mouse models of pancreas development.Proc. Natl. Acad. Sci. USA200410192924292910.1073/pnas.030860410014970313
     [Google Scholar]
  24. In't VeldP MarichalM. Microscopic anatomy of the human islet of Langerhans. In: The islets of LangerhansSpringer201010.1007/978‑90‑481‑3271‑3_1
     [Google Scholar]
  25. BreretonM.F. VergariE. ZhangQ. ClarkA. Alpha-, delta-and PP-cells: are they the architectural cornerstones of islet structure and co-ordination?J. Histochem. Cytochem.201563857559110.1369/002215541558353526216135
     [Google Scholar]
  26. FrantzE. Souza-MelloV. Mandarim-de-LacerdaC. Pancreas: Anatomy, diseases and health implications. pancreas anatomy.Dis. Heal. Implicat.201245152
     [Google Scholar]
  27. BergmanR.N. Orchestration of glucose homeostasis: from a small acorn to the California oak.Diabetes20075661489150110.2337/db07‑990317526912
     [Google Scholar]
  28. GuoL. LiQ. WangW. YuP. PanH. LiP. SunY. ZhangJ. Apelin inhibits insulin secretion in pancreatic β-cells by activation of PI3-kinase-phosphodiesterase 3B.Endocr. Res.200934414215410.3109/0743580090328707919878074
     [Google Scholar]
  29. Corb AronR.A. AbidA. VesaC.M. NechiforA.C. BehlT. GhiteaT.C. MunteanuM.A. FratilaO. Andronie-CioaraF.L. TomaM.M. BungauS. Recognizing the benefits of pre-/probiotics in metabolic syndrome and type 2 diabetes mellitus considering the influence of Akkermansia muciniphila as a key gut bacterium.Microorganisms20219361810.3390/microorganisms903061833802777
     [Google Scholar]
  30. MomiN. KaurS. KrishnS.R. BatraS.K. Discovering the route from inflammation to pancreatic cancer.Minerva Gastroenterol. Dietol.201258428329723207606
     [Google Scholar]
  31. LippmanS.M. Abate-ShenC. Colbert MaressoK.L. ColditzG.A. DannenbergA.J. DavidsonN.E. DisisM.L. DuBoisR.N. SzaboE. GiulianoA.R. HaitW.N. LeeJ.J. KenslerT.W. KramerB.S. LimburgP. MaitraA. MartinezM.E. RebbeckT.R. SchmitzK.H. VilarE. HawkE.T. AACR white paper: shaping the future of cancer prevention–a roadmap for advancing science and public health.Cancer Prev. Res.2018111273577810.1158/1940‑6207.CAPR‑18‑042130530635
     [Google Scholar]
  32. Al NeimatKS. AlserhanyAK. AlanaziME. AlanaziAA. AlanaziNE. AlanaziMA. AlmulhimFA. AlazmiIA. AlanaziAQ. AlsharariAS. AlsharariMM. Updates in prevalence, risk factors, management and outcome of treatment of acute pancreatitis.Pharmacophore202213417
     [Google Scholar]
  33. ChauhanS. GuptaS. YasminS. SainiM. Antihyperglycemic and antioxidant potential of plant extract of Litchi chinensis and Glycine max.Int. J. Nutr. Pharmacol. Neurol. Dis.2021113225233
     [Google Scholar]
  34. DhankarS. MujwarS. GargN. ChauhanS. SharmaP. Kumar SharmaS. KamalM.A. RaniD.N. KumarS. SainiM. Artificial intelligence in the management of neurodegenerative disorders.CNS Neurol. Disord. Drug Targets202323893194037861051
     [Google Scholar]
  35. ZhaoZ. LiuW. Pancreatic cancer: A review of risk factors, diagnosis, and treatment.Technol. Cancer Res. Treat.20201910.1177/153303382096211733357065
     [Google Scholar]
  36. BienE. BarthlenW. BrechtIB. SiposB. Pancreatic Tumors. In: Rare tumors in children and adolescentsSpringer International Publishing202210.1007/978‑3‑030‑92071‑5_28
     [Google Scholar]
  37. TabishS.A. Is diabetes becoming the biggest epidemic of the twenty-first century?Int. J. Health Sci.200712VVIII21475425
     [Google Scholar]
  38. FeuchtbaumL. CarterJ. DowrayS. CurrierR.J. LoreyF. Birth prevalence of disorders detectable through newborn screening by race/ethnicity.Genet. Med.2012141193794510.1038/gim.2012.7622766612
     [Google Scholar]
  39. PappV. MagyariM. AktasO. BergerT. BroadleyS.A. CabreP. JacobA. KiraJ. LeiteM.I. MarignierR. MiyamotoK. PalaceJ. SaizA. SepulvedaM. SveinssonO. IllesZ. Worldwide incidence and prevalence of neuromyelitis optica: A systematic review.Neurology2021962597710.1212/WNL.000000000001115333310876
     [Google Scholar]
  40. MederosM.A. ReberH.A. GirgisM.D. Acute Pancreatitis.JAMA2021325438239010.1001/jama.2020.2031733496779
     [Google Scholar]
  41. YadavD. WhitcombD.C. The role of alcohol and smoking in pancreatitis.Nat. Rev. Gastroenterol. Hepatol.20107313114510.1038/nrgastro.2010.620125091
     [Google Scholar]
  42. SchererJ. SinghV.P. PitchumoniC.S. YadavD. Issues in hypertriglyceridemic pancreatitis: An update.J. Clin. Gastroenterol.201448319520310.1097/01.mcg.0000436438.60145.5a24172179
     [Google Scholar]
  43. SinghiA.D. PaiR.K. KantJ.A. BartholowT.L. ZehH.J. LeeK.K. WijkstromM. YadavD. BottinoR. BrandR.E. ChennatJ.S. LoweM.E. PapachristouG.I. SlivkaA. WhitcombD.C. HumarA. The histopathology of PRSS1 hereditary pancreatitis.Am. J. Surg. Pathol.201438334635310.1097/PAS.000000000000016424525505
     [Google Scholar]
  44. BanksP.A. ConwellD.L. ToskesP.P. The management of acute and chronic pancreatitis.Gastroenterol. Hepatol. (N. Y.)201062Suppl. 311620567557
     [Google Scholar]
  45. GuidelinesA.A. IAP/APA evidence-based guidelines for the management of acute pancreatitis.Pancreatology2013134Suppl. 2e1e1510.1016/j.pan.2013.07.06324054878
     [Google Scholar]
  46. KylänpääL. RakonczayZ.Jr O’ReillyD.A. The clinical course of acute pancreatitis and the inflammatory mediators that drive it.Int. J. Inflamm.20122012136068523304633
     [Google Scholar]
  47. LippiG. ValentinoM. CervellinG. Laboratory diagnosis of acute pancreatitis: in search of the Holy Grail.Crit. Rev. Clin. Lab. Sci.2012491183110.3109/10408363.2012.65835422339380
     [Google Scholar]
  48. JamesW. Gastrointestinal Pathologies, Dysfunctions, and Disorders. In: Mosby's Pathology for Massage Professionals-E-BookElsevier2021
     [Google Scholar]
  49. HinesO.J. PandolS.J. Management of severe acute pancreatitis.BMJ2019367l622710.1136/bmj.l622731791953
     [Google Scholar]
  50. BeyerG. HoffmeisterA. LorenzP. LynenP. LerchM.M. MayerleJ. Clinical practice guideline—acute and chronic pancreatitis.Dtsch. Arztebl. Int.202211929-3049550135945698
     [Google Scholar]
  51. CampbellJ. Is pancreatic exocrine insufficiency an under-recognised diagnosis?Doctoral dissertation, University of Sheffield.
     [Google Scholar]
  52. PonikowskiP. AnkerS.D. AlHabibK.F. CowieM.R. ForceT.L. HuS. JaarsmaT. KrumH. RastogiV. RohdeL.E. SamalU.C. ShimokawaH. Budi SiswantoB. SliwaK. FilippatosG. Heart failure: preventing disease and death worldwide.ESC Heart Fail.20141142510.1002/ehf2.1200528834669
     [Google Scholar]
  53. LangfordR.M. Pain management today—what have we learned?Clin. Rheumatol.200625S1Suppl. 12810.1007/s10067‑006‑0311‑516741780
     [Google Scholar]
  54. TomlinM. Intravenous fluid management.Clin Pharm. J.2018101210.1211/PJ.2018.2020567
     [Google Scholar]
  55. LarsenJA. Enteral nutrition and tube feeding. In: Applied veterinary clinical nutrition.Wiley202310.1002/9781119375241.ch20
     [Google Scholar]
  56. WuG. MaY. WeiW. ZengJ. HanY. SongY. WangZ. QianW. Ondansetron: Recommended antiemetics for patients with acute pancreatitis? A population-based study.Front. Pharmacol.202314115539110.3389/fphar.2023.115539137234720
     [Google Scholar]
  57. LammertF. GurusamyK. KoC.W. MiquelJ.F. Méndez-SánchezN. PortincasaP. van ErpecumK.J. van LaarhovenC.J. WangD.Q.H. Gallstones.Nat. Rev. Dis. Primers2016211602410.1038/nrdp.2016.2427121416
     [Google Scholar]
  58. MeierR. OckengaJ. PertkiewiczM. PapA. MilinicN. MacFieJ. LöserC. KeimV. ESPEN guidelines on enteral nutrition: Pancreas.Clin. Nutr.200625227528410.1016/j.clnu.2006.01.01916678943
     [Google Scholar]
  59. ShyuJ.Y. SainaniN.I. SahniV.A. ChickJ.F. ChauhanN.R. ConwellD.L. ClancyT.E. BanksP.A. SilvermanS.G. Necrotizing pancreatitis: diagnosis, imaging, and intervention.Radiographics20143451218123910.1148/rg.34513001225208277
     [Google Scholar]
  60. HussainZ. ThuH.E. AmjadM.W. HussainF. AhmedT.A. KhanS. Exploring recent developments to improve antioxidant, anti-inflammatory and antimicrobial efficacy of curcumin: A review of new trends and future perspectives.Mater. Sci. Eng. C2017771316132610.1016/j.msec.2017.03.22628532009
     [Google Scholar]
  61. ShahrajabianM.H. SunW. ChengQ. The power of natural Chinese medicine, ginger and ginseng root in an organic life.Middle East J. Sci. Res.20192716471
     [Google Scholar]
  62. MittalP. DhankharS. ChauhanS. GargN. BhattacharyaT. AliM. ChaudharyA.A. RudayniH.A. Al-ZharaniM. AhmadW. KhanS.U.D. SinghT.G. MujwarS. A review on natural antioxidants for their role in the treatment of Parkinson’s disease.Pharmaceuticals (Basel)202316790810.3390/ph1607090837513820
     [Google Scholar]
  63. MeratS. KhaliliS. MostajabiP. GhorbaniA. AnsariR. MalekzadehR. The effect of enteric-coated, delayed-release peppermint oil on irritable bowel syndrome.Dig. Dis. Sci.20105551385139010.1007/s10620‑009‑0854‑919507027
     [Google Scholar]
  64. SándorZ. MottaghipishehJ. VeresK. HohmannJ. BencsikT. HorváthA. KelemenD. PappR. BarthóL. CsuporD. Evidence supports tradition: The in vitro effects of roman chamomile on smooth muscles.Front. Pharmacol.2018932310.3389/fphar.2018.0032329681854
     [Google Scholar]
  65. LalitK. NavpreetK. SamratC. RandhirS. Phyto-pharmacological review of Coccinia indica.World J. Pharm. Pharm. Sci.20143217341745[WJPPS].
     [Google Scholar]
  66. PistónM. MachadoI. BrancoC.S. CesioV. HeinzenH. RibeiroD. FernandesE. ChistéR.C. FreitasM. Infusion, decoction and hydroalcoholic extracts of leaves from artichoke ( Cynara cardunculus L. subsp. cardunculus ) are effective scavengers of physiologically relevant ROS and RNS.Food Res. Int.20146415015610.1016/j.foodres.2014.05.07830011634
     [Google Scholar]
  67. MurrayMT. Glycyrrhiza glabra (licorice). In: Textbook of Natural MedicineElsevier2020
     [Google Scholar]
  68. GardnerTB. AdlerDG. ForsmarkCE. SauerBG. TaylorJR. WhitcombDC. ACG clinical guideline: chronic pancreatitis.Off. J. Am. Coll. Gastroenterol.2020115332233910.14309/ajg.0000000000000535
     [Google Scholar]
  69. EtemadB. WhitcombD.C. Chronic pancreatitis: Diagnosis, classification, and new genetic developments.Gastroenterology2001120368270710.1053/gast.2001.2258611179244
     [Google Scholar]
  70. HardimanO. Al-ChalabiA. ChioA. CorrE.M. LogroscinoG. RobberechtW. ShawP.J. SimmonsZ. Van Den BergL.H. Amyotrophic lateral sclerosis.Nat. Rev. Dis. Primers20173119
     [Google Scholar]
  71. ChristodoulouD.K. TsianosE.V. Role of endoscopic retrograde cholangiopancreatography in pancreatic diseases.World J. Gastroenterol.201016384755476110.3748/wjg.v16.i38.475520939103
     [Google Scholar]
  72. Kovacheva-SlavovaMD. GetsovPG. VladimirovGB. VladimirovBG. Up-to-date view on the clinical manifestations and complications of chronic pancreatitis. In: PancreatitisIntechOpen201910.5772/intechopen.84738
     [Google Scholar]
  73. MukherjeePK. Quality control and evaluation of herbal drugs: Evaluating natural products and traditional medicine.Elsevier2019
     [Google Scholar]
  74. ChauhanS. KishoreL. KaurN. SinghR. Potential anti-arthritic agents from Indian medicinal plants.Res. Rev.2015431022
     [Google Scholar]
  75. MaR.H. NiZ.J. ZhuY.Y. ThakurK. ZhangF. ZhangY.Y. HuF. ZhangJ.G. WeiZ.J. A recent update on the multifaceted health benefits associated with ginger and its bioactive components.Food Funct.202112251954210.1039/D0FO02834G33367423
     [Google Scholar]
  76. ValussiM. Functional foods with digestion-enhancing properties.Int. J. Food Sci. Nutrit.201263S1828910.3109/09637486.2011.627841
     [Google Scholar]
  77. MatosLC. MachadoJP. MonteiroFJ. GretenHJ. Understanding traditional Chinese medicine therapeutics: an overview of the basics and clinical applications. In: HealthcareMDPI202110.3390/healthcare9030257
     [Google Scholar]
  78. GiuglianoD. CerielloA. EspositoK. The effects of diet on inflammation: emphasis on the metabolic syndrome.J. Am. Coll. Cardiol.200648467768510.1016/j.jacc.2006.03.05216904534
     [Google Scholar]
  79. BoydJ.E. LaniusR.A. McKinnonM.C. Mindfulness-based treatments for posttraumatic stress disorder: A review of the treatment literature and neurobiological evidence.J. Psychiatry Neurosci.201843172510.1503/jpn.17002129252162
     [Google Scholar]
  80. KleeffJ. KorcM. ApteM. La VecchiaC. JohnsonC.D. BiankinA.V. NealeR.E. TemperoM. TuvesonD.A. HrubanR.H. NeoptolemosJ.P. Pancreatic cancer.Nat. Rev. Dis. Primers2016211602210.1038/nrdp.2016.2227158978
     [Google Scholar]
  81. McGuiganA. KellyP. TurkingtonR.C. JonesC. ColemanH.G. McCainR.S. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes.World J. Gastroenterol.201824434846486110.3748/wjg.v24.i43.484630487695
     [Google Scholar]
  82. QianD. ZhangT. ZhengP. LiangZ. WangS. XieJ. ZhaoL. ZhangY. SituB. Comparison of oral antidiabetic drugs as add-on treatments in patients with type 2 diabetes uncontrolled on metformin: A network meta-analysis.Diabetes Ther.2018951945195810.1007/s13300‑018‑0482‑530121726
     [Google Scholar]
  83. RifshanaF. BrehenyM. TaylorJ.E. RossK. The parental experience of caring for a child with type 1 diabetes.J. Child Fam. Stud.201726113226323610.1007/s10826‑017‑0806‑5
     [Google Scholar]
  84. DubeyKG. The Indian cuisine. In: PHI Learning Pvt. Ltd.2010
     [Google Scholar]
  85. LambrinouE. HansenT.B. BeulensJ.W.J. Lifestyle factors, self-management and patient empowerment in diabetes care.Eur. J. Prev. Cardiol.2019262_supplSuppl.556310.1177/204748731988545531766913
     [Google Scholar]
  86. MalpassA. AndrewsR. TurnerK.M. Patients with Type 2 Diabetes experiences of making multiple lifestyle changes: A qualitative study.Patient Educ. Couns.200974225826310.1016/j.pec.2008.08.01818848413
     [Google Scholar]
  87. HaywardN.J. McDougallG.J. FaragS. AllwoodJ.W. AustinC. CampbellF. HorganG. RanawanaV. Cinnamon shows antidiabetic properties that are species-specific: Effects on enzyme activity inhibition and starch digestion.Plant Foods Hum. Nutr.201974454455210.1007/s11130‑019‑00760‑831372918
     [Google Scholar]
  88. SrinivasaU.M. NaiduM.M. Fenugreek (Trigonella foenum-graecum L.) seed: promising source of nutraceutical.Stud. Nat. Prod. Chem.20217114118410.1016/B978‑0‑323‑91095‑8.00014‑3
     [Google Scholar]
  89. MisraA.M. LalanM.S. SinghV.K. GovilJ.N. Role of natural polysaccharides in treatment and control of diabetes. Chemistry and medicinal value.Recent Progr Med Plants.200925347373
     [Google Scholar]
  90. RatanZ.A. HaidereM.F. HongY.H. ParkS.H. LeeJ.O. LeeJ. ChoJ.Y. Pharmacological potential of ginseng and its major component ginsenosides.J. Ginseng Res.202145219921010.1016/j.jgr.2020.02.00433841000
     [Google Scholar]
  91. AlnajjarM. Kumar BarikS. BestwickC. CampbellF. CruickshankM. FarquharsonF. HoltropG. HorganG. LouisP. MoarK.M. RussellW.R. ScobbieL. HoggardN. Anthocyanin-enriched bilberry extract attenuates glycaemic response in overweight volunteers without changes in insulin.J. Funct. Foods20206410359710.1016/j.jff.2019.103597
     [Google Scholar]
  92. KanmazH. GokceY. HayalogluA.A. Volatiles, phenolic compounds and bioactive properties of essential oil and aqueous extract of purple basil (Ocimum basilicum L.) and antidiabetic activity in streptozotocin-induced diabetic Wistar rats.Food Chem. Adv.2023310042910.1016/j.focha.2023.100429
     [Google Scholar]
  93. WittH. Chronic pancreatitis and cystic fibrosis.Gut200352Suppl 2ii31ii4112651880
     [Google Scholar]
  94. HegyiP. WilschanskiM. MuallemS. LukacsG.L. Sahin-TóthM. UcA. GrayM.A. RakonczayZ.Jr MaléthJ. CFTR: a new horizon in the pathomechanism and treatment of pancreatitis.Rev. Physiol. Biochem. Pharmacol.2016170376610.1007/112_2015_500226856995
     [Google Scholar]
  95. Lopes-PachecoM. CFTR modulators: the changing face of cystic fibrosis in the era of precision medicine.Front. Pharmacol.202010166210.3389/fphar.2019.0166232153386
     [Google Scholar]
  96. PatelL. Assessing self efficacy in caregivers of children with cystic fibrosis.Doctoral dissertation, University of Liverpool.
     [Google Scholar]
  97. HartP.A. ZenY. ChariS.T. Recent advances in autoimmune pancreatitis.Gastroenterology20151491395110.1053/j.gastro.2015.03.01025770706
     [Google Scholar]
  98. AbrahamM. KhosroshahiA. Diagnostic and treatment workup for IgG4-related disease.Expert Rev. Clin. Immunol.201713986787510.1080/1744666X.2017.135469828701054
     [Google Scholar]
  99. OkazakiK. KawaS. KamisawaT. ShimosegawaT. TanakaM. Japanese consensus guidelines for management of autoimmune pancreatitis: I. Concept and diagnosis of autoimmune pancreatitis.J. Gastroenterol.201045324926510.1007/s00535‑009‑0184‑x20084528
     [Google Scholar]
  100. Ven MurthyMR. RanjekarP. RamassamyC. DeshpandeM. Scientific basis for the use of Indian ayurvedic medicinal plants in the treatment of neurodegenerative disorders: 1. Ashwagandha.Cent. Nervous Sys. Agent. Med. Chem.2010103238246
     [Google Scholar]
  101. LambaA. OakesA. RobertsL. DepreleS. NogajL. Correlating indigenous peruvian women’s distance to cusco and their access to healthcare, and investigating the effect of Cat’s claw extracts on HeLa cells.FASEB J.201933S149149310.1096/fasebj.2019.33.1_supplement.491.3
     [Google Scholar]
  102. AggarwalB.B. YuanW. LiS. GuptaS.C. Curcumin free turmeric exhibits anti inflammatory and anticancer activities: Identification of novel components of turmeric.Mol. Nutr. Food Res.20135791529154210.1002/mnfr.20120083823847105
     [Google Scholar]
  103. ShenP. JiaoY. MiaoL. ChenJ. Momtazi-BorojeniA.A. Immunomodulatory effects of berberine on the inflamed joint reveal new therapeutic targets for rheumatoid arthritis management.J. Cell. Mol. Med.20202421122341224510.1111/jcmm.1580332969153
     [Google Scholar]
  104. MehtaS. SharmaA.K. SinghR.K. Pharmacological activities and molecular mechanisms of pure and crude extract of Andrographis paniculata: An update.Phytomedicine Plus20211410008510.1016/j.phyplu.2021.100085
     [Google Scholar]
  105. HannanM.A. RahmanM.A. SohagA.A.M. UddinM.J. DashR. SikderM.H. RahmanM.S. TimalsinaB. MunniY.A. SarkerP.P. AlamM. MohibbullahM. HaqueM.N. JahanI. HossainM.T. AfrinT. RahmanM.M. Tahjib-Ul-ArifM. MitraS. OktavianiD.F. KhanM.K. ChoiH.J. MoonI.S. KimB. Black cumin (Nigella sativa L.): A comprehensive review on phytochemistry, health benefits, molecular pharmacology, and safety.Nutrients2021136178410.3390/nu1306178434073784
     [Google Scholar]
  106. ParasuramanS. Anand DavidA.V. ArulmoliR. Overviews of biological importance of quercetin: A bioactive flavonoid.Pharmacogn. Rev.20161020848910.4103/0973‑7847.19404428082789
     [Google Scholar]
  107. HafnerA. LovrićJ. LakošG.P. PepićI. Nanotherapeutics in the EU: an overview on current state and future directions.Int. J. Nanomedicine201491005102324600222
     [Google Scholar]
  108. SharmaS. KumariN. GargD. ChauhanS. A compendium of bioavailability enhancement via niosome technology.Pharm. Nanotechnol.202311432433810.2174/221173851166623030910432336892113
     [Google Scholar]
  109. KennerB. ChariS.T. KelsenD. KlimstraD.S. PandolS.J. RosenthalM. RustgiA.K. TaylorJ.A. YalaA. Abul-HusnN. AndersenD.K. BernsteinD. BrunakS. CantoM.I. EldarY.C. FishmanE.K. FleshmanJ. GoV.L.W. HoltJ.M. FieldB. GoldbergA. HoosW. Iacobuzio-DonahueC. LiD. LidgardG. MaitraA. MatrisianL.M. PobleteS. RothschildL. SanderC. SchwartzL.H. ShalitU. SrivastavaS. WolpinB. Artificial intelligence and early detection of pancreatic cancer: 2020 summative review.Pancreas202150325127910.1097/MPA.000000000000176233835956
     [Google Scholar]
/content/journals/cnf/10.2174/0115734013307659240820060042
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Beyond Insulin: A Deeper Dive into Pancreatic Disease
Curr. Nutr. Food Sci. 21, 265 (2025); https://doi.org/10.2174/0115734013307659240820060042
/content/journals/cnf/10.2174/0115734013307659240820060042
/content/journals/cnf/10.2174/0115734013307659240820060042
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  • Article Type:     Review Article
Keyword(s): glandular organ; herbal; pancreas; Pancreatic diseases; pancreatic neoplasms; treatment

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