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Volume 20, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
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Abstract

Aim

To investigate the performance of a novel radiological-metabolic scoring (RM-S) system to predict mortality and intensive care unit (ICU) requirements among COVID-19 patients and to compare performance with the chest computed-tomography severity-scoring (C-CT-SS). The RM-S was created from scoring systems such as visual coronary-artery-calcification scoring (V-CAC-S), hepatic-steatosis scoring (HS-S) and pancreatic-steatosis scoring (PS-S).

Methods

Between May 2021 and January 2022, 397 patients with COVID-19 were included in this retrospective cohort study. All demographic, clinical and laboratory data and chest CT images of patients were retrospectively reviewed. RM-S, V-CAC-S, HS-S, PS-S and C-CT-SS scores were calculated, and their performance in predicting mortality and ICU requirement were evaluated by univariate and multivariable analyses.

Results

A total of 32 (8.1%) patients died, and 77 (19.4%) patients required ICU admission. Mortality and ICU admission were both associated with older age ( < 0.001). Sex distribution was similar in the deceased survivor and ICU non-ICU comparisons ( = 0.974 and = 0.626, respectively). Multiple logistic regression revealed that mortality was independently associated with having a C-CT-SS score of ≥ 14 ( < 0.001) and severe RM-S category ( = 0.010), while ICU requirement was independently associated with having a C-CT-SS score of ≥ 14 ( < 0.001) and severe V-CAC-S category ( = 0.010).

Conclusion

RM-S, C-CT-SS, and V-CAC-S are useful tools that can be used to predict patients with poor prognoses for COVID-19. Long-term prospective follow-up of patients with high RM-S scores can be useful for predicting long COVID.

© 2024 Bentham Science Publishers
© 2024 The Author(s). Published by Bentham Science Publisher. This is an open access article published under CC BY 4.0 https://creativecommons.org/licenses/by/4.0/legalcode
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2023-05-24
2024-11-23

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A Novel Combined Model to Predict the Prognosis of COVID-19: Radiological-metabolic Scoring
Curr. Med. Imaging 20, e110523216780 (2024); https://doi.org/10.2174/1573405620666230511093259
/content/journals/cmir/10.2174/1573405620666230511093259
/content/journals/cmir/10.2174/1573405620666230511093259
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  • Article Type:     Research Article
Keyword(s): Chest computed tomography severity scoring; Coronary artery calcification; COVID-19; Hepatic steatosis; Intensive care unit; Pancreatic steatosis; Radiological-metabolic scoring

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