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Volume 21, Issue 1
  • ISSN: 1573-4056
  • E-ISSN: 1875-6603
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Abstract

Background

Cytomegalovirus (CMV) infection is common in the digestive and central nervous systems and can infect the entire digestive tract from the mouth to the rectum. In immunocompromised patients, CMV infection is prone to develop into CMV disease, especially in Acquired Immune Deficiency Syndrome (AIDS) patients. Severe cases may accelerate the progression of AIDS patients and form systemic CMV infection. Timely diagnosis and treatment are very important for the prognosis of patients.

Case Presentation

In this paper, we report a 36-year-old man with a Human Immunodeficiency Virus (HIV) infection complicated with CMV colitis. Three weeks ago, he developed abdominal pain with fresh blood in the stool, accompanied by anal pain. He was found to be HIV positive 8 years ago. An enhanced CT scan showed edema and irregular thickening of the rectal wall, obvious enhancement of the mucosa, and multiple enlarged lymph nodes around. 18F-FDG PET/CT imaging displayed diffuse rectum wall thickening and increased glucose metabolism, and the SUV max was 12.7. There were multiple enlarged lymph nodes around the rectum, glucose metabolism was increased, and the SUVmax was 4.6.

Conclusion

18F-FDG-PET imaging technology has potential value in the diagnosis of CMV colitis, especially in immunocompromised patients. Detection of FDG concentrations in the colon wall can help diagnose CMV infection and understand the extent of the lesion, which is essential for the timely initiation of antiviral therapy.

© 2025 The Author(s). Published by Bentham Science Publishers.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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2025-01-01
2025-05-11

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/content/journals/cmir/10.2174/0115734056361753241226065721
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HIV Infection Complicated with Cytomegalovirus Colitis: A Case Report of 18F-FDG PET/CT Imaging
Curr. Med. Imaging 21, e15734056361753 (2025); https://doi.org/10.2174/0115734056361753241226065721
/content/journals/cmir/10.2174/0115734056361753241226065721
/content/journals/cmir/10.2174/0115734056361753241226065721
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  • Article Type:     Case Report
Keyword(s): 18F-FDG; Acquired immune deficiency syndrome; Case report; Colitis; Cytomegalovirus; Human immunodeficiency virus; PET/CT

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