Full text loading...
- ISSN: 1389-2029
- E-ISSN: 1875-5488
-
Mitochondria and Familial Predisposition to Breast Cancer
- Source: Current Genomics, Volume 14, Issue 3, May 2013, p. 195 - 203
-
- 01 May 2013
Abstract
Mitochondrial genome and functional alterations are related to various diseases including cancer. In all cases, the role of these organelles is associated with defects in oxidative energy metabolism and control of tumor-induced oxidative stress. The present study examines the involvement of mitochondrial DNA in cancer and in particular in breast cancer. Furthermore, since mitochondrial DNA is maternally inherited, hereditary breast cancer has been focused on.
© Bentham Science Publishers