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- Volume 13, Issue 3, 2021
Current Drug Research Reviews - Volume 13, Issue 3, 2021
Volume 13, Issue 3, 2021
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Potential of Antibiotics for the Treatment and Management of Parkinson's Disease: An Overview
Authors: Narayan Yadav, Ajit K. Thakur, Nikhila Shekhar and AyushiEvidence has emerged over the last 2 decades to ascertain the proof of concepts viz. mitochondrial dysfunction, inflammation-derived oxidative damage and cytokine-induced toxicity that play a significant role in Parkinson's disease (PD). The available pharmacotherapies for PD are mainly symptomatic and typically indicate L-DOPA to restrain dopamine deficiency and its consequences. In the 21st century, the role of antibio Read More
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Therapeutic Potential of Green Synthesized Metallic Nanoparticles Against Staphylococcus aureus
Authors: Meron M. Tsegaye, Garima Chouhan, Molla Fentie, Priya Tyagi and Parma NandBackground: The recent treatment challenges posed by the widespread emergence of pathogenic multidrug-resistant (MDR) bacterial strains cause huge health problems worldwide. Infections caused by MDR organisms are associated with longer periods of hospitalization, increased mortality, and inflated healthcare costs. Staphylococcus aureus is one of these MDR organisms identified as an urgent threat to human health by t Read More
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Potential Drugs for the Treatment of COVID-19: Synthesis, Brief History and Application
Coronaviruses (CoVs) belong to the Betacoronavirus group, an unusually large RNA genome characterized by club-like spikes that project from their surface. An outbreak of a novel coronavirus 2019 (nCOVID-19) already showed a unique replication strategy and infection that has posed significant threat to international health and the economy around the globe. Scientists around the world are investigating few previously used clinic Read More
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A Review on Repurposed Drugs and Vaccine Trials for Combating SARS CoV-2
Authors: Nikita Khanna, Sandip V. Pawar and Anil KumarBackground: The novel coronavirus disease 2019 (COVID-19), emerged in Wuhan, China in December 2019 and then spread worldwide rapidly. The records from World Health Organisation (WHO), Centres of Disease Control and Prevention (CDC) and Food and Drug Administration (FDA) backup the fact that no medications have proven to be completely effective for prevention or treatment of SARS-CoV-2. The clinical trials are un Read More
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Cosmeceutical Aptitudes of Azelaic Acid
Authors: Supriya K. Singh, Saumya Chaubey, Anil Bansal, Gurpreet Kaur and Deepinder Singh MalikAzelaic acid (AZA) is a white crystalline dicarboxylic acid naturally found in grains, rye, and barley. AZA has substantial biological and therapeutic abilities (viz a viz) its anti-inflammatory, anti-oxidant, anti-keratinizing, anti-microbial properties, etc., which contribute to its applicability in the management of mild to harsh dermatological complications (acne, rosacea, dermatitis, hyper-pigmentation, carcinomas, etc.). AZA has Read More
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Substance Use Portrayal in Oscar-nominated Movies
Background: As one of the forms of media and art most consumed in the world, Oscar- nominated movies should have their drug use representation monitored because of possibly influencing but also reflecting society’s behavior. Objective: The present study aims to investigate drug use representation in scenes from movies nominated for the Academy Awards (Oscar) from 2008-2011 through media content an Read More
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Effect of BMI on Prolonged Abstinence after Smoking Cessation Treatment: A Retrospective Cohort Study
Background: Despite the well-documented relationship between weight gain and poorer cessation outcomes among smokers, the role of the former (baseline) weight in smoking cessation is insufficiently investigated. We hypothesized that patients with higher baseline body mass index( BMI) have a worse prognosis in tobacco cessation. Objectives: This retrospective clinical cohort study aimed to investigate the role of th Read More
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