Current Drug Metabolism - Volume 18, Issue 10, 2017

Background: Honey is known for its therapeutic properties from ancient civilizations. Recently, the mechanism of action of Manuka honey in wound healing, epithelial regeneration, and ulcer treatments has been revealed. Objective: In the current review, the health perspectives of honey, its chemical composition with special reference to flavonoids, polyphenol, and other bioactive trace compounds used in tissue regeneration Read More

Background: Several disease conditions require controlled or sustained drug release leading to complete recovery. In recent years, there has been a considerable research interest in bio-inspired biomaterials due to their potential as an alternative to the traditional synthetic counterparts. Methods: Herein, we extensively reviewed, analyzed and compiled salient information from the authentic bibliographic databases includi Read More

Background: Polyphenols are plant secondary metabolites present in the human and animal diet, and numerous studies have demonstrated the beneficial effects of polyphenol-rich ingredients. Methods: To date, the research for natural antioxidants as alternative to synthetic products is of great interest among scientists. The present review emphasizes the importance of knowing the content and the quality of phenolic com Read More

Background: Poly (lactic acid) (PLA) based novel constructs have been engineered for targeted applications in various biomedical sectors of the modern world. In this context, a special focus has been given to pharmaceutical and cosmeceutical industries. Methods: In this review, we extensively reviewed, analyzed and compiled salient information from the authentic bibliographic sources including PubMed, Scopus, Els Read More

Background: Angiogenesis is an essential physiological process for growth and maintenance of the body. Especially its role becomes indispendable during the embryonic development stage but lacks in adults with some exceptions like while wound repair and menstrual cycle. It is a tightly regulated process and relies on the cascade of several molecular signaling pathways with the involvement of many effectors like vascul Read More

Background: Viruses are the most devastating pathogens of almost all life forms including humans and animals. Viruses can replicate very fast and may affect any metabolic and physiological function of the host cell. Therefore, it has been a challenge to develop a universal and common treatment against viral pathogens, in contrast to bacterial pathogens. Virus-host interaction is a complex phenomenon and often is virus Read More