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- Volume 1, Issue 1, 2021
Current Chinese Science - Volume 1, Issue 1, 2021
Volume 1, Issue 1, 2021
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Identifying Native and Non-native Membrane Protein Loops by Using Stabilizing Energetic Terms of Three Popular Force Fields
Authors: Konda M. Saravanan, Haiping Zhang and Yanjie WeiBackground: Predicting the three-dimensional structure of globular proteins from their amino acid sequence has reached a fair accuracy, but predicting the structure of membrane proteins, especially loop regions, is still a difficult task in structural bioinformatics. The difficulty in predicting membrane loops is due to various factors like length variation, position, flexibility, and they are easily prone to mutation. Objective: In th Read More
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Exploring Structure-function Relationship of Two-dimensional Electrocatalysts with Synchrotron Radiation X-ray Absorption Spectrum
Authors: Nan Zhang, Wenjie Wang, Tianpei Zhou, Yangchao Tian and Wangsheng ChuTwo-dimensional (2D) nanomaterials with unique anisotropy and electronic properties are deemed as an ideal platform for establishing clear relationships between structure and catalytic reactivity. Knowledge of their structures is essential for understanding the catalytic behavior, which further facilitates the development of high-performance catalysts. In this review, we focus on the recent progress of synchrotron radiati Read More
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Amine Structure-Foam Behavior Relationship and Its Predictive Foam Model Used for Amine Selection for Design of Amine-based Carbon Dioxide (CO2) Capture Process
Authors: Pailin Muchan, Jessica Narku-Tetteh, Teeradet Supap and Raphael IdemBackground: The use of an amine solution to capture CO2 from flue gases is one of the methods applied commercially to clean up the exhaust gas stream of a power plant. One of the issues in this process is foaming which should be known in order to select a suitable amine for design. Objectives: In this work, all possible types of amines used for CO2 capture, namely, alkanolamines, sterically hindered alkanolamines, m Read More
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Identification of Functional Variants Associated with Obesity in Pakistani Kindred
Authors: Ayesha Aftab, Syed B. Jamal and Syeda Marriam BakhtiarBackground: Obesity is an emerging pandemic considered to be an outcome of change in lifestyle owing to more processed food and the use of mechanical locomotives. Obesity has not only appeared as a problem in the esthetic appearance of an individual rather is a serious health issue due to its associations with various chronic diseases such as coronary and cardiovascular problems, hypertension, osteoarthritis, type-II Read More
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In vitro Assay Revealed Mismatches between Guide RNA and Target DNA can Enhance Cas9 Nuclease Activity
Authors: Ji Luan, Zhen Li, Hailong Wang, Jun Fu and Youming ZhangBackground: CRISPR-Cas9 is a powerful technology that allows us to modify DNA sequences in a specific manner across a variety of organisms. Due to its high efficiency and specificity, and ease of use, it becomes a commonly used method for gene editing. Although many structural and biochemical studies have been carried out to understand the fundamental mechanism of CRISPR/Cas9, our understanding of CRISPR/Ca Read More
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Functional Role of Mangrove Forests Along the Subtropical and Tropical Coasts of China
More LessMangroves forests inhabiting the south coast of China are crucial habitats for the functioning of the coastal zone. This role has not been carefully considered in China and compared to their functional role worldwide. China’s mangroves currently occupy 20,303 ha. Average forest biomass is equivalent to the global average, but the mean ratio of below-ground to above-ground biomass is high (46%), reflecting the young age o Read More
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Simulation Analysis on Genomic Selection of Grouper (Epinephelus coioides) Breeding for Categorical Traits
Authors: Zhiyuan Ma and Xinxin YouBackground: The basic principle of genome selection (GS) is to establish a model of genome estimated breeding value (GEBV) by using single-nucleotide polymorphisms (SNPs) covering the entire genome. Despite the decreasing cost of high-throughput genotyping, the GS strategy remains expensive due to the need for phenotyping and genotyping for a large number of samples. Simulation analysis of genome selection is a Read More
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