Current Chemical Biology - Volume 13, Issue 1, 2019

Background: There are many different tools for diagnostics of various diseases. One of the simplest approach for the early, rapid and accurate diagnosis represents determination of biomarkers. Focus: In the following text, we describe review of the latest discoveries in the field of biomarkers of selected diseases: intestinal ischemia and atherosclerosis. The aim of this review article is to show the problems which th Read More

Background: Mitochondrial diseases are a complex group of pathologies caused by mutations in genes coded in the nuclear and/or the mitochondrial DNA, which fulfill their function in the organelle. The diagnosis is also complex, since it depends on the integration of biochemical, histological and imaging data. Objective: In this paper we review the use of some of these substances and their efficacy in the treatment Read More

Background: Microbiological quality of food is of utmost importance in the food industry, so the use of food additives is essential to reduce microbial loads, which may result in food spoilage and poisoning. Objective: This study aimed to test the antimicrobial activity of three natural compounds – chitosan, ethanolic extract of propolis, and nisin – against 15 Gram-positive bacteria, 15 Gram-negative bacteria and two fungi and, also, Read More

Objective: Deep sea water (DSW) accumulates many scientific shreds of evidence in treating obesity. Previous studies indicated that it reduces white adipose tissue (WAT) and body weight. WAT is energy storage fat, while beige adipose tissue is energy supply fat. In this study, the effects of DSW in the induction of beige adipocytes from mouse adipose tissue-derived stromal vascular fraction (SVF) cells are determined. Meth Read More

Background: Trimethylamine-N-Oxide (TMAO) is a small organic molecule derived from the metabolism of L-carnitine and choline after ingestion of animal food. TMAO has many functions such as electron acceptor, an osmolyte, stabilizer of macromolecules folding. It seems that TMAO plays an important role in nature but, in humans, it is a remnant of the evolution of the osmolyte system. Objective: The present paper is address Read More

Background: The combination of Fourier Transform InfraRed and levitation techniques, both on levitated water mixtures of Polyethylene Glycols (PEG)s and on wood finds, allows to follow the polymeric drying process as a function of time through the O-H and C-H stretching contributions and to investigate the wood thermal response. Objective: The aim of this paper is to report the FTIR investigations on wood fines, extracted f Read More

Background: Plant parasitic nematodes are dangerous pests that damage various agricultural crops and decrease their productivity. Objective: The resistance of new lines of wheat (Triticum aestivum L.) plants obtained under in vitro conditions on MS media containing microbial bioregulators to plant parasitic nematodes was studied under in vitro and greenhouse conditions. Methods: Here we conducted physiological and molecu Read More

Background: Cellulolysis is of considerable economic importance in laundry detergents, textile and pulp and paper industries and in fermentation of biomass into biofuels. Objective: The aim was to screen cellulase producing actinobacteria from the fruit orchard because of its requirement in several chemical reactions. Methods: Strains of actinobacteria were isolated on Sabouraud's agar medium. Similarities in cultural and bi Read More