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- Volume 20, Issue 7, 2024
Current Bioactive Compounds - Volume 20, Issue 7, 2024
Volume 20, Issue 7, 2024
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Optimization and Transfollicular Delivery of Finasteride Loaded PLGA Nanoparticles Laden Carbopol Gel for Treatment of Hair Growth Stimulation
Authors: Mounika Kuchukuntla, Venkatesan Palanivel and Madhubabu AnanthulaBackground: One of the frequent side effects of cancer treatment is chemotherapyinduced alopecia (CIA). The psychological discomfort of hair loss may cause patients to stop receiving chemotherapy, lowering the therapy's effectiveness. Finasteride (FNS), a JAK inhibitor, has shown tremendous promise in therapeutic uses for treating baldness. Still, systemic side effects constrained its broad use in alopecia from oral treatment a Read More
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Pyridazine (1, 2-diazine): A Versatile Pharmacophore Known for its Utility in Biological Systems
By Swati SharmaThe present review describes the biological essence of pyridazine scaffold. Around 142 biologically potential pyridazine entities are gathered in a pile from documented literature. Some of them are commercially available drugs, few are naturally occurring pyridazine compounds, and a wide variety of compounds containing pyridazine moiety are biologically tested, and some are under clinical trials. Rather than collecting larg Read More
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Natural Polysaccharides Derived from Fruits and Mushrooms with Anti-inflammatory and Antioxidant Effects
A large class of substances known as polysaccharides have a wide range of advantageous therapeutic and nutritional properties. Polysaccharides found in plants and plant components are extracted for the use in treating a number of diseases. Since ancient times, these polysaccharides have been utilized for human wellness. With no or minimal adverse effects, the polysaccharides that were extracted and refined from the frui Read More
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Wide-ranging Study on Synthesis and Biological Evaluation of 1, 2, 3-triazole
Authors: Anshu Dudhe, Rupesh Dudhe, Renuka Mahajan, Neha Pathak, Vaibhav Uplanchiwar and Mohammad H. Mansoori1, 2, 3-traizole is five-membered heterocyclic compounds having three nitrogen at 1, 2 and 3 positions. 1, 2, 3-triazoles are important five-membered heterocyclic scaffolds due to their widespread biological activities. 1, 2, 3-triazole derivative can be readily obtained in good to excellent yields through click chemistry, 1, 3-dipolar cycloaddition, Metal Catalysed azide-alyne cycloaddition method. 1, 2, 3-triazoles showed vari Read More
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Theaflavins Induce Autophagy in Ehrlich’s Ascites Carcinoma Cells both In vivo and In vitro
Aims: To investigate the autophagy-inducing and tumoricidal efficacy of Theaflavins on Ehrlich’s Ascites Carcinoma (EAC) cells. Background: The apoptosis-inducing role of Theaflavins against cancer is reported. Autophagy, a cellular mechanism under stress, occurs either as a survival process or Type-II programmed-cell death in the presence/absence of apoptosis. The report of Theaflavins inducing autophagy against cancer is Read More
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Volumes & issues
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Volume 21 (2025)
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Volume 20 (2024)
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Volume 19 (2023)
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Volume 18 (2022)
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Volume 17 (2021)
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Volume 16 (2020)
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Volume 15 (2019)
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Volume 14 (2018)
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Volume 13 (2017)
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Volume 12 (2016)
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Volume 11 (2015)
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Volume 10 (2014)
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Volume 9 (2013)
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Volume 8 (2012)
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Volume 7 (2011)
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Volume 6 (2010)
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Volume 5 (2009)
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Volume 4 (2008)
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Volume 3 (2007)
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Volume 2 (2006)
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Volume 1 (2005)
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Podophyllotoxin: Current Perspectives
Authors: Ying Qian Liu, Liu Yang and Xuan Tian
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