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Volume 2, Issue 1
  • ISSN: 1573-4072
  • E-ISSN: 1875-6646

Abstract

In this review we critically examine PI (Padmakar-Ivan) index of organic compounds acting as drugs and discussed its applications in Computer-Aided designing of bioactive compounds with special reference to designing of carbonic anhydrase inhibitors, lipophilicity, toxicity, tadpole narcosis, bio-concentration factor, diuretic activity and carcinogenic activity of aromatic hydrocarbons and heterocycles etc.

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/content/journals/cbc/10.2174/1573407210602010019
2006-03-01
2025-05-24

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  • Article Type:     Research Article
Keyword(s): anhydrace inhibitor; bioactive compound; carbonic; computer-aided drug design; lipophilicity; PI index; QSAR; QSPR; QSTR; regression analysis

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