Current Aging Science - Volume 16, Issue 3, 2023

Age-related macular degeneration (ARMD or AMD) is a progressive, sight-threatening disease. The pathogenesis of ARMD is complex, involving many factors, such as metabolic, functional, genetic, and environmental factors. Recently, long interspersed nuclear element-1 (L1)– mediated reverse transcription (RT) of Alu RNA into cytoplasmic Alu complementary DNA (cDNA) has been associated with retinal pigment epitheli Read More

Background: Parkinson's disease is a complicated, gradually progressive neurological illness characterized by locomotor and non-motor symptomatology that impedes daily activities. Despite significant advances in symptomatic therapies with various extents of negative effects, there are currently no disease-modifying medicinal alternatives. Symptoms worsen, creating an additional strain that reduces living quality an Read More

Populations are ageing at varying rates of development. Countries with developed economies have experienced such changes to their population structures. Examinations have been conducted with regard to how respective societies can accommodate the said changes in their health and social systems, but this research mostly focuses on more developed regions rather than lowerincome countries. This paper discussed th Read More

The presence of sarcopenia and obesity is a feature of sarcopenic obesity (SO). In this condition, the fat-to-lean body mass ratio is incorrect. Excess visceral fat, the percentage of body fat, subcutaneous fat, and body mass index causes poor health and premature death and has been linked to conditions such as type 2 diabetes, ischemic heart disease, high blood pressure, and several types of cancer. In addition, control, autono Read More

Background: Self-defining future projections (SDFP) are mental representations of plausible and highly significant future events that provide core information of one’s understanding of self. Objective: We explored SDFPs in a large sample of older adults and aimed to target the interrelations between the main dimensions of SDFPs. Moreover, correlations between these dimensions and clinical and cognitive variables were exa Read More

Background: The relationship between environmental diversity and the health status of older adults has been less considered in studies. This study seeks to investigate the causal relationship among the environment, falling, fear of falling, and the imbalance of older adults in southern Iran in 2021. Objective: The investigation into the relationship between environmental pollution to the imbalance and fear of falling, especially i Read More

Introduction: The time spent in different physical activity (PA) intensities is associated with sarcopenia risk for community-dwelling older women. Aim: To evaluate the role of sitting time and physical activity (PA) level as predictors of sarcopenia odds. Methods: In a cross-sectional study, physically independent older women (n = 67) performed the six-minute walk test to identify functional limitation (≤ 400 m). Sedentary ti Read More

Background: With age, there is a tendency for the health of law enforcement officers to deteriorate. This especially applies to instructor officers, whose professional activity is characterized by a significant decrease in the volume of motor activity, overloading of the intellectual sphere, and high neuro-emotional stress. Objective: The aim of the research is to investigate the influence of recreational and healthpromoting traini Read More

Background: MLC601 and MLC901 showed neuroprotective and neuroregenerative properties and positive results in the treatment of dementia and cognitive impairment. This study aimed to investigate the long-term benefits of monotherapy with MLC601 and MLC901 in patients with Alzheimer's disease (AD). Methods: In this study, patients with AD, diagnosed by DSM-IV criteria, were enrolled. Patients have received MLC601 for f Read More

Background: Increasing age and the added disadvantage of diabetic peripheral neuropathy (DPN) put the individual at a higher risk of falls and reduced functional fitness. However, there is a dearth of literature on multifactorial balance intervention, especially targeting the needs of older adults with DPN. Objective: The current study aimed to determine the effect of a multifactorial balance rehabilitation program on fall ris Read More