Current Alzheimer Research - Volume 19, Issue 8, 2022

Objectives: This study aimed to explore whether bilingual older adults had a cognitive advantage over their monolingual counterparts, and validate the influence of cognition-related (participants’ cognitive condition, the cognitive domain assessed), and bilingualism-related factors (second language proficiency, frequency of use, acquisition time, and immigration status of participants)on the cognitive advantage of bilingualis Read More

Dementia has been characterized by atypical neurological syndromes and several cognitive deficits, such as extended memory loss, strange behavior, unusual thinking, impaired judgment, impotence, and difficulty with daily living activities. Dementia is not a disease, but it is caused by several neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and Lewy’s bodies. Several drugs and remedies are indicated for Read More

Background: As the number of older adults in Ghana keeps increasing, so does the prevalence of aging-related diseases and conditions that tend to lead to cognitive decline. However, knowledge on the predicting factors of healthcare utilization among older adults with cognitive limitations is still scarce. Objective: This study examines the predictive factors of healthcare-seeking behavior among older adults with moderate-to-seve Read More

Background: Overt sentence reading in mild cognitive impairment (MCI) and mild-tomoderate Alzheimer’s disease (AD) has been associated with slowness of speech, characterized by a higher number of pauses, shorter speech units and slower speech rate and attributed to reduced working memory/ attention and language capacity. Objective: This preliminary case-control study investigates whether the temporal organization Read More

Background: Quantitative measures of atrophy on structural MRI are sensitive to the neurodegeneration that occurs in AD, and the topographical pattern of atrophy could serve as a sensitive and specific biomarker. Objective: We aimed to examine the distribution of cortical atrophy associated with cognitive decline and disease stage based on quantitative structural MRI analysis in a Chinese cohort to inform clinical diagnosis an Read More