Current Analytical Chemistry - Volume 8, Issue 3, 2012

Ionizing radiation used for sterilization of drugs may lead to drug degradation and therefore essential element of the validation process is the choice of optimal conditions for sterilization, i.e. radiation dose and radiation source. This investigation examines and compares radiostability of derivatives of 1-phenylpropan-1-ol exposed to the same effective doses of ionizing radiation but emitted from different sources: gamma Read More

Introduction: Cigarette smoking causes devastating disease worldwide. Current cigarette classification is based on standardised tar mass values obtained from smoking-machines. However, their ability to predict disease is poor, and these mass values are primarily determined by larger particles. The aim of our study is to investigate in how far claimed tar values also reflect smaller tar particles in cigarette smoke. Method Read More

A micro/nanostructured composite electrode was constructed by introducing various portions of aluminum titanate nanopowder and gold nanoparticle into glassy carbon paste electrode and used for glutathione (GSH) detection. After the optimization of experimental parameters, the analytical characteristics of the developed system were investigated. Two linear ranges between 5-50 μM and 100-750 μM with the equa Read More

A method based on coprecipitation of Cr (III) with copper-violuric acid for the preconcentration/speciation of Cr (III) and Cr (VI) has been developed. While Cr (III) was quantitatively recovered, Cr (VI) was recovered under 15 % level at pH 6. Total Cr was determined with reducing of Cr (VI) to Cr (III) with concentrated sulphuric acid and ethanol. The concentration of Cr (VI) was calculated by the concentration difference between t Read More

A whole cell based biosensor is prepared by immobilizing Chlorella sp. microbes over glassy carbon electrode. The proposed biosensor is optimized for characteristics like; substrate concentration, pH, response time, durability, etc. The electrode responds linearly in concentration range of 10-14 M to 10-6 M for zinc, copper, cadmium, cobalt and nickel ions. Relative selectivity of the metal ions can be ordered in following sequence Read More

A new dispersive liquid–liquid microextraction based on solidification of floating organic drop (DLLMESFO)/ flow injection-spectrophotometry (FI) method for simultaneous separation and preconcentration of trace amounts of copper and zinc was developed. 1-(2-pyridylazo)-2-naphthol (PAN), 1-undecanol and acetonitrile were used as chelating agent, extraction solvent and disperser solvent, respectively. The factors influencin Read More

A sensitive kinetic-spectrophotometic method for the simultaneous determination of antibiotics in a mixture, specifically of amikacin (AMK), gentamicin (GTM) and etimicin (ETM), has been researched and developed with the use of reaction kinetics. 1,2-naphthoquinone-4-sulphonate (NQS) was used as the derivative reagent to produce colored products in a medium of pH 9.02, and their spectra were collected in orde Read More

A series of new sensors (1, 2, 3 and 4) bearing aromatic hydroxyl group shows the strongest binding ability for AcO- by UV-vis, fluorescence, 1H NMR titrations and theoretical investigation. The sensitivity for AcO- can be tuned by electron push-pull properties of the substituents on the aromatic ortho position of the sensor. Especially, sensor 4 containing nitro group shows the best sensitivity. The excellent sensitivity of 4 Read More

The increasing industrial demand for lipases has lead to the identification of new sources of enzymes with unique properties and generated a great interest in applying rapid, reliable, specific, selective, and sensitive analytical methods for evaluating their catalytic activity. This work offers a professional look on the achievements and the emerging strategies for lipases activity determination, involving volumetry, spectrometry Read More

Evaluations of adulteration, geographical and botanical origin of bee-products are matters of great interest worldwide. These trends are principally related to the international market of food commodities. The chemometric tools appear as new analytical complements which, in recent years, were successfully used to define the geographical and botanical origin of food raw materials or to detect possible adulterations. The clas Read More