Current Analytical Chemistry - Volume 18, Issue 7, 2022

Background: Demand for alcohol-based products, including gel- and aqueous-type hand sanitizers, room sprays, and mouthwashes, has rapidly increased during the ongoing COVID-19 pandemic because of their microbicidal properties. However, toxic methanol can be found from the intentional addition of methanol by manufacturers and invariable production during the manufacturing of alcohol (ethanol). Although th Read More

Background: By using bimetal nanocomposite modified electrode, the electrochemical DNA biosensor showed the advantages of high sensitivity, low cost, rapid response and convenient operation, which was applied for disease diagnosis, food safety, and biological monitoring. Objective: A nanocomposite consisting of platinum (Pt)-gold (Au) bimetal and two-dimensional graphene (GR) was synthesized by hydrothermal meth Read More

Aims: Here, we report a simple strategy for the preparation of thermally exfoliated graphite (EG) and its application to modify glassy carbon electrode (GCE) surfaces for electrochemical Cu2+ ion sensing. Method: The electrochemical Cu2+ sensor was constructed by a layer modification of a glassy carbon electrode (GCE) with exfoliated graphite (EG) and chitosan (CS) as a binder, and CS also supports a large number of - Read More

Background: 5-Fluorouracil (5-FU) is a well-established anticancer drug. Several studies have also demonstrated the anticancer potential of Cannabidiol (CBD) against various malignancies, including skin cancer. Reported synergistic effects of this combination fascinate researchers to consider this for the management of skin cancer. Methods: A simple and robust HPLC method for simultaneous estimation of 5-FU and C Read More

Background: Uric acid (UA) is an important metabolic intermediate of the human body. Abnormally high levels of UA will cause diseases. However, UA monitoring with commercial products relies on invasive blood collection, which not only causes pain in patients but also risks bacterial infections and skin irritation. In recent years, new models of noninvasive detection through body surface penetration have raised higher expectati Read More

Background: Currently, carbon nanomaterials and carbon nanomaterials-based electrodes have illustrated significant electrocatalytic abilities. Methods: An electrochemical sensor was developed for vanillin using graphene (GR) decorated with gold nanoparticles (AuNPs) on a glassy carbon electrode (GCE) with two steps. AuNPs/GR/GCE, as the electrochemical sensor for determination of vanillin, included dropping GR onto th Read More

Background: Recent studies demonstrate that titanium dioxide nanoparticles (TiO2 NPs) are an effective source of reactive oxygen species (ROS) for photodynamic therapy and radionuclide stimulated dynamic therapy (RaST). Unfortunately, tracking the in vivo distribution of TiO2 NPs noninvasively remains elusive. Objective: Given the use of gadolinium (Gd) chelates as effective contrast agents for magnetic resonance Read More

Background: Water contamination and its remediation are currently considered a major concern worldwide. Design of effective methods for water purification is highly demanded for the adsorption and removal of such pollutants. Objective: This study depicts the effectiveness of nickel oxide-copper oxide nanoparticles (NiO-CuO), which can extract and remediate ferric ions, Fe(III), from aqueous solutions. Methods: The NiO-C Read More

Background: Detection of Vitamin C (Vc) is very important to protect human health. A lot of methods have been developed for the detection of Vc. However, many methods require complex material preparation and skilled operators. Thus, a simple, label-free biosensor is still urgently needed. Methods: In this work, N-methylmesoporphyrin IX (NMM)/G-quadruplex pair was used as a labelfree signal reporter. Without Vc, the G-qu Read More

Background: A rapid and specific detection of pathogens is of great importance from public health viewpoint as well as from economic perspectives. Genosensor based on sequence specific detection of Escherichia coli facilitates significant improvements in rapidity and specificity over traditional microbiological methods. Objective: The present study was aimed at identifying a sequence of xanQ genetic markers for Read More