Anti-Infective Agents - Volume 21, Issue 5, 2023

Bryophyllum pinnatum, commonly known as the "patharchatta," belongs to the family of "Crassulaceae." Bryophyllum pinnatum is often used to treat gallbladder stones and heal wounds. It possesses a lot of pharmacological properties, such as antioxidant, anti-cancerous, antimicrobial, antiviral, etc. It is an aromatic plant having a sweet and sour smell and is used as a herb. In different plant species, essential oils present Read More

Antibiotic resistance was described soon after the discovery of penicillin by Fleming. In recent years, there has been an increasing interest in developing alternatives to solve this problem. Propolis «Bee glue» has been used by humans in folk medicine since ancient times, it is a natural resinous mixture produced by honeybees (Apis mellifera) from collected parts of plants. Many studies reported that the phytochemical c Read More

Human immunodeficiency virus (HIV) is the cause of acquired immunodeficiency syndrome (AIDS), an immunosuppressive, life-threatening condition that frequently results in other potentially fatal opportunistic infections in affected patients. Despite advancements in anti-retroviral therapy, AIDS remains the main reason for worldwide mortality. Although various anti-HIV drugs have profoundly enhanced the quality o Read More

Antibiotic-resistant illnesses are on the rise worldwide, and the pipeline for developing new antibiotics is drying up. As a result, researchers need to create novel compounds with antimicrobial action. Recent decades have seen a dearth of novel antibiotics because of the reliance on conventional empirical screening procedures using both natural and synthetic chemicals to find them. There is hope that the massive amount of bact Read More

Background: Since the outbreak of the COVID-19 pandemic in 2019, the world has been racing to develop effective drugs for treating this deadly disease. Although there are now some vaccines that have somewhat alleviated global panic, the lack of approved drugs remains a persistent challenge. Consequently, there is a pressing need to discover new therapeutic molecules.Methods: In this study, we explore the applicati Read More

Background: Herpes simplex Virus type 1 (HSV-1) is a contagious human pathogen causing severe infection. In recent decades, the virus has become dormant and resistant to available treatment creating the need for the development of new therapeutic agents against it. Benzotriazole is a versatile molecule with a wide range of activities like antibacterial, antiprotozoal, antiulcer, anthelmintic, and antiproliferative activity. Read More

Background: Linalool is a known anti-fungal molecule. It could be a good candidate against oropharyngeal candidiasis if its retention in deeper skin layers, specifically at body temperature, can be extended for a long duration.Aim: We aimed to develop and evaluate a linalool liposome-based mucoadhesive gel.Objective: The objective of this study is to improvise localization in oral mucosa by achieving sustained release, ensuri Read More

The article entitled "Analytical Method Development and Validation for Determination of Assay of Antibacterial Drugs Besifloxacin Hydrochloride and Phenoxyethanol in Gel Formulation", by Pradeep Kundu, Neelam Pawar, Neha Minocha and Asha Poonia, published in Anti-Infective Agents 2023; 21(4): e310323215342. https://dx.doi.org/10.2174/2211352521666230331111623.The corresponding author of this article submitt Read More