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Volume 23, Issue 1
  • ISSN: 2211-3525
  • E-ISSN: 2211-3533

Abstract

Gastrointestinal parasites have become the most common reason for infection in humans, affecting many people in the world. Helminthic infections pose a large threat to public health in developing countries. The most common parasites of helminths in humans are whipworms (), roundworms (), tapeworms (), and hookworms ( and ). In the current scenario, synthetic medicines are found to be effective in curing the infection but these medicines produce side-effects that impair the effectiveness of the treatment. Fortunately, in the traditional system of medicines various medicinal plants have been mentioned for their anthelmintic activities, which are relatively free from side effects and are used by ethnic groups worldwide. In the 21st century, an ideal anthelmintic agent should be cost-effective, provide a high percentage of cure, have a broad spectrum of action, and free from toxicity to the host. However, none of the modern marketed medicines fulfill these requirements. Therefore, in this view, several researchers have undertaken various and studies to scrutinize folklore medicinal plants for their proclaimed anthelmintic activity. In this review, we have summarized some scientifically approved polyherbal formulations and Indian medicinal plants documented for anthelmintic activity, which can be further studied to achieve novel herbal lead molecules from them by isolating their principal compounds.

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2025-01-26

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/content/journals/aia/10.2174/0122113525304411240528074154
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A Review of Traditional Anthelmintic Approaches: Exploring Medicinal Plants and Polyherbal Formulations for Effective and Safe Gastrointestinal Parasite Treatment
Anti Infect. Agents 23, E250624231302 (2025); https://doi.org/10.2174/0122113525304411240528074154
/content/journals/aia/10.2174/0122113525304411240528074154
/content/journals/aia/10.2174/0122113525304411240528074154
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  • Article Type:     Review Article
Keyword(s): ancylostoma duodenale; anthelmintic activity; Ascaris lumbricoides; Helminthic infections; medicinal plants; Necator americanus; polyherbal formulations; Taenia solium; Trichuris trichiura

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