Recent Advances in Drug Delivery and Formulation - Volume 18, Issue 3, 2024

The liposomal drug delivery system is considered an advanced drug delivery technology for formulating lipid core nano-structured particles using lipids from natural and synthetic sources. Liposomes play a wide role in improving drugs with less solubility and greater toxicity profile. Liposomes have numerous advantages, such as enhanced drug loading, good biocompatibility, prolonged drug release profile, and better pharmac Read More

Cancer refers to a condition in which abnormal cells uncontrollably divide, resulting in the destruction of tissues. In colorectal cancer, uncontrolled cell proliferation takes place in the rectum or colon. Most colorectal tumors start as adenomas, a form of polyp that can develop into cancer within the rectum or colon. Symptoms of colorectal cancer include chronic diarrhea or constipation, bleeding from the rectum, bloody stools, c Read More

Micellar systems, particularly polymeric micelles, have emerged as a promising drug delivery vehicle for water-insoluble compounds. Polymeric micelles, self-assembled nanostructures made from amphiphilic block copolymers, have emerged as a promising drug delivery vehicle for water-insoluble compounds. These micelles offer high drug loading capacity, stability, and the ability to solubilize large amounts of hydrophobic Read More

Background: Solid dispersion is a common technique used for solubility enhancement of poorly soluble drugs. Objective: In this study, loratadine (LOR), a class II biopharmaceutical classification system (BCS), was formulated as solid dispersion tablets using modified Ziziphus spina-christi gum (MZG) as a carrier. Methods: The solvent evaporation method was used for LOR-MZG solid dispersion (SD) preparation. A variety of tests Read More