Comparative Study on Synthesis and Biological, Pharmaceutical Applications of Aromatic Substituted Chalcones

Chalcones(1, 3, diaryl-2-propen-1-ones) are prominent compounds and therefore, various procedures have been worked out for their synthesis. This review highlights the synthesis and pharmacological properties of chalcone derivatives. Chalcones are flavonoids that have been studied extensively for their medicinal and biological properties. These chalcone derivatives have shown important antimalarial, anticancer, antimicrobial, anti-inflammatory, antioxidant, antituberculosis, anticonvulsant, antileishmanial, and anti-HIV properties. The new structural classes of compounds may prove to be lead molecules and good candidates for future investigations.