DNA, PNA, and Their Derivatives for Precise Genotyping of SNPs

A. Kuzuya; J.- M. Zhou; M. Komiyama

doi:10.2174/1570193043488999

ISSN: 1570-193X
E-ISSN:

DNA, PNA, and Their Derivatives for Precise Genotyping of SNPs
Authors: A. Kuzuya¹, J.- M. Zhou² and M. Komiyama³
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Affiliations: ¹ Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8904 Japan. ² Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8904 Japan. ³ Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8904 Japan.
Source: Mini-Reviews in Organic Chemistry, Volume 1, Issue 1, Jan 2004, p. 125 - 131
DOI: https://doi.org/10.2174/1570193043488999
- Available online: 01 Jan 2004

Abstract

Two new approaches for SNP genotyping are described. The one is based on tandem site-selective RNA scission and the genotype is determined by MALDI-TOF / MS analyses of clipped short RNA. The other is visual SNP genotyping with combinations of peptide nucleic acid (PNA) and single-stranded DNA specific nucleases.

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2004-01-01

2024-10-17

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Article Type: Review Article

Keyword(s): acridine; nuclease; pna; rna; selective scission; snp genotyping

DNA, PNA, and Their Derivatives for Precise Genotyping of SNPs

Abstract

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