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2000
Volume 17, Issue 16
  • ISSN: 1389-5575
  • E-ISSN: 1875-5607

Abstract

Objective: The spirooxindole heterocyclic scaffold is found in many natural products and has been identified as an important bioactive agent. Background: Over the past few decades, various spirooxindole-containing compounds have been reported to possess biological properties and hence found in the structure of many synthetic pharmaceuticals. This mini-review describes the most promising examples of this class of compounds possessing biological activity including anticancer, anti-inflammatory, and antimicrobial activities. Conclusion: The current review focuses on the biological activity of compounds containing the spirooxindole scaffold.

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/content/journals/mrmc/10.2174/1389557516666160624125108
2017-11-01
2025-07-12
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  • Article Type:
    Research Article
Keyword(s): Biological importance; chemistry; heterocycles; pharmacophores; spirooxindoles; synthesis
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