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Perspectives on the Development of Novel Potentially Active Quinolones Against Tuberculosis and Cancer
- Source: Mini Reviews in Medicinal Chemistry, Volume 12, Issue 9, Aug 2012, p. 866 - 874
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- 01 Aug 2012
Abstract
Quinolones and its derivatives comprise an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as antibacterial, antitumor, antiviral, anti-ischemic, antiparasitic and anxiolytic. Persistent efforts have been made over the years to develop novel congeners with superior biological activities and minimal potential for undesirable side-effects. The present review aims to highlight some recent discoveries on the development of novel quinolone-based compounds with potential antitubercular and anticancer activity.
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