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Recent Advances in Synthesis of PAR Ligands as Therapeutic Strategy for Inflammatory Diseases
- Source: Mini Reviews in Medicinal Chemistry, Volume 9, Issue 6, Jun 2009, p. 653 - 663
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- 01 Jun 2009
Abstract
Several studies have been published on discovering involvement of PARs receptors in a number of disease states, including cancer and inflammation of the cardiovascular, respiratory, musculoskeletal, gastrointestinal and nervous systems. This mini-review will focus on recent advances in the synthesis of PAR ligands highlighting their therapeutic potential in the treatment of various inflammatory diseases.
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