Skip to content
2000
Volume 7, Issue 8
  • ISSN: 1389-5575
  • E-ISSN: 1875-5607

Abstract

The main function of the innate immune system from insects to mammals is to detect the presence of and act against invading microorganisms by recognizing their unique molecular signatures, most importantly, components of bacterial cell walls. A large number of peptides and derivatives, both synthetic and of natural origin, are known to influence immune responses in mammals by interacting with the conserved microbial structures, making the former attractive targets for drug development. This review focuses on structural aspects of the immunomodulating peptides and their receptors, including primary constitution, stereochemistry, conformation, binding and hydrophobic properties.

Loading

Article metrics loading...

/content/journals/mrmc/10.2174/138955707781387957
2007-08-01
2025-06-19
Loading full text...

Full text loading...

/content/journals/mrmc/10.2174/138955707781387957
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test