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Tumor Suppression by DNA Base Excision Repair
- Source: Mini Reviews in Medicinal Chemistry, Volume 7, Issue 7, Jul 2007, p. 727 - 743
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- 01 Jul 2007
Abstract
Base excision repair (BER) is the main pathway for repair of endogenous DNA damage. It was expected that different tumor types could derive from BER defects but to date this link is elusive. In vitro and molecular epidemiology studies may be used to unravel this issue.
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