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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Natural and Synthetic Cholera Toxin Antagonists
- Source: Mini Reviews in Medicinal Chemistry, Volume 7, Issue 2, Feb 2007, p. 159 - 170
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- 01 Feb 2007
Abstract
Cholera Toxin (CT) recognizes the cell membrane through specific interactions with ganglioside GM1. Recent structural elucidation of the CT/GM1 complex has allowed the rational design of artificial receptors for the toxin, which could function as anti-cholera drugs. The efforts towards the rational design of Cholera Toxin inhibitors will be presented.
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