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- ISSN: 1389-5575
- E-ISSN: 1875-5607
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Recent Advances in the Development of Agonists Selective for β1-Type Thyroid Hormone Receptor
- Source: Mini Reviews in Medicinal Chemistry, Volume 7, Issue 1, Jan 2007, p. 79 - 86
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- 01 Jan 2007
Abstract
This mini-review will provide an overview on the recent design principles and structure-activity-relationship of β-selective thyroid hormone receptor (TR) agonists. The prospects for the treatment of metabolic diseases as dyslipidemia with TRβ-selective ligands are considerable enough so as to avoid cardiovascular acceleration mediated through TRα.
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