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2000
Volume 7, Issue 1
  • ISSN: 1389-5575
  • E-ISSN: 1875-5607

Abstract

This mini-review will provide an overview on the recent design principles and structure-activity-relationship of β-selective thyroid hormone receptor (TR) agonists. The prospects for the treatment of metabolic diseases as dyslipidemia with TRβ-selective ligands are considerable enough so as to avoid cardiovascular acceleration mediated through TRα.

© Bentham Science Publishers
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/content/journals/mrmc/10.2174/138955707779317885
2007-01-01
2025-07-28

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  • Article Type:     Research Article
Keyword(s): beta-selective; cholesterol; heart rate; metabolic rate; Nuclear hormone receptors; structure-activity-relationship (SAR); thyroid hormones agonists; thyroid hormones receptors; X-ray

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