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Currently Available Drugs for the Treatment of Obesity: Sibutramine and Orlistat
- Source: Mini Reviews in Medicinal Chemistry, Volume 7, Issue 1, Jan 2007, p. 3 - 10
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- 01 Jan 2007
Abstract
The currently available drugs for long-term treatment of obesity are sibutramine and orlistat. They have been shown to be able to induce significant weight loss, with important co-morbidity reduction, allowing the maintenance of reduced body weight for at least 1-2 years. Cardiostimulating and gastrointestinal adverse effects are however not negligible.
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